97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
911视频播放器,美日一级毛片,无码国产精品一区二区VR
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-GCM2/Cy5.5 Conjugated antibody (bs-13314R-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13314R-Cy5.5
英文名稱 Rabbit Anti-GCM2/Cy5.5 Conjugated antibody
中文名稱 Cy5.5標記的絨毛膜特異性轉錄因子GCM2抗體
別    名 Chorion-specific transcription factor GCMb; GCM motif protein 2; GCMb; Glial cells missing homolog 2; glial cells missing homolog b; GCM2_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  發育生物學  干細胞  轉錄調節因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Horse, Rabbit, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 57kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GCM2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Glial cells missing homolog 2 (GCM2), also known as Chorion-specific transcription factor GCMb, is a 506 amino acid nuclear protein. GCM2 is a transcription factor that acts as an essential regulator of parathyroid development. GCM2 is also thought to mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. GCM2 contains one N-terminal GCM domain, which has DNA binding activity. Mutations of the gene that encodes GCM2 are associated with hypoparathyroidism, an autosomal recessive condition characterized by hypocalcemia and hyperphosphatemia.

Function:
Gcm2, a mouse ortholog of the Drosophila Glial Cells Missing gene, is expressed in the parathyroid-specific domains in the 3rd pouches from E9.5. The null mutation of Gcm2 causes aparathyroidism in the fetal and adult mouse and has been proposed to be a master regulator for parathyroid development. During Drosophila embryogenesis Gcm2 plays a crucial role in promoting glial cell differentiation.

Subcellular Location:
Nuclear.

DISEASE:
Defects in GCM2 are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]; also known as autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. An autosomal recessive form of FIH also exists.

Similarity:
Contains 1 GCM DNA-binding domain.

Database links:

Entrez Gene: 9247 Human

Omim: 603716 Human

SwissProt: O75603 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 无码AV免费一区二区三区四区 | www.草草草| 91免费| 精品国产免费久久久久久尖叫 | 人妻aⅴ中文字幕无码 | 伊人75在线 | 麻豆影音 | 无码AV免费一区二区三区四区 | 古典武侠激情亚洲精品一区 | 久久久一区二区三区 | 国产www网站| 欧美在线视屏 | 欧美另类综合 | 乱人伦人成品精国产在线 | 91精品国产91久久 | 三级黄色的视频 | 免费羞羞视频无遮挡噼啪男男 | 精品国产精品久久一区免费式 | 久久精品一级爱片 | MM131午夜福利在线观看 | 天天草网站 | 国产成年无码久久久免费 | 成熟人妻换╳╳╳╳ | 久久国产午夜精品理论片推荐 | 欧美日韩在线视频 | 中文字幕AV无码免费一区 | 九一视频国产 | 一级少妇性生话片 | 亚洲精品无码久久久久AV老牛 | 亚洲自偷自偷图片 | 色视频www在线播放国产人成 | 中文字幕一区二区三区av | 视频一区视频二区国产精品 | 97精品一区二区三区 | 欧美性受xxxx黑人x丫x性爽 | 亚洲一区二区精彩视频 | 欧美人与猪马狗在线观看 | av最新天| 久久狠狠色噜噜狠狠狠狠97 | 狂野欧美激情性XXXX按摩 | 日韩一二三区在线 |