97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
日韩av免费播放,美女一级毛片免费视频,91丨porny丨最新
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-HBP1/Cy3 Conjugated antibody (bs-15418R-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-15418R-Cy3
英文名稱 Rabbit Anti-HBP1/Cy3 Conjugated antibody
中文名稱 Cy3標記的HMG盒區內含蛋白1抗體
別    名 FLJ16340; HBP 1; HBP1; HBP1_HUMAN; High mobility group box transcription factor 1; HMG box containing protein 1; HMG box transcription factor 1; HMG box-containing protein 1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 心血管  染色質和核信號  干細胞  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 58kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HBP1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
HBP1 is a member of the HMG family of transcription factors, which are characterized by the presence of a conserved protein motif, the high mobility group (HMG) 1 box, that mediates DNA binding. HBP-1 binds to the tumor suppressor proteins Rb and p130 and initiates cell cycle arrest.Terminal cell differentiation requires this initial cell cycle arrest followed by the coordinated expression of genes defined as tissue-specifc markers. Along with initiating the commitment to cell differentiation, the continued activity of HBP1 abrogates the expression of tissue-specific genes by associating with the MyoD proteins. In muscle cell differentiation, the MyoD family of transcription factors, which include Myf5, MyoD and myogenein, induce the expression of these cell-type specific proteins and contribute to the development of cell phenotypes. The progression of terminal differentiation is, therefore, dependent on both a decrease in HBP1 activity and the corresponding activation of MyoD-induced gene transcription.

Function:
Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

Subunit:
Binds the second PAH repeat of SIN3A (By similarity). Binds TCF4 and RB1.

Subcellular Location:
Nucleus.

Similarity:
Contains 1 AXH domain.
Contains 1 HMG box DNA-binding domain.

Database links:

Entrez Gene: 26959 Human

Entrez Gene: 73389 Mouse

Entrez Gene: 27080 Rat

SwissProt: O60381 Human

SwissProt: Q8R316 Mouse

SwissProt: Q62661 Rat

Unigene: 162032 Human

Unigene: 390461 Mouse

Unigene: 458534 Mouse

Unigene: 89226 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 国产色爽女 | 国产真实乱偷精品视频免 | 国产一区欧美二区 | 一区二区视频免费看 | 国产一区三 | 色综合精品无码一区二区三区 | 免费碰碰视频在线观看 | YY111111少妇影院免费观看 | 欧美日韩高清一区二区三区 | 久久精品人妻无码一区二区三区 | 粉嫩AV一区二区夜夜嗨 | 天堂综合网久久 | 在线观看成年人免费视频 | 国产一级片大全 | 久久男女 | 免费人成免费观看视频 | 久久久综合久久 | 在线免费观看一区二区 | 亚洲欧美日韩综合在线丁香 | 亚洲欧洲无码一区二区三区 | 国产熟女AA级毛片 | 日本黄色片在线免费观看 | 欧美专区在线 | 久久亚洲国产精品五月天婷 | 久久人人槡人妻人人玩夜色AV | 国产免费一区二区在线a片视频 | 久久国产激情视频 | 又黄又粗暴的120秒免费GIF视频 | 日本aⅴ日本高清视频影片www | 欧美xxxx做受性欧美88 | 不卡一二区 | 岳好紧好湿夹太紧了好爽 | 亚洲高清无吗 | 国产资源第一页 | 国产乱码在线 | www.九九九| www.日韩有码 | 奶头和荫蒂添的好舒服囗交 | 免费av无码无在线观看 | 最新的黄色网址 | 91看大片|