97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
黄色自拍偷拍,成人久草,人妻无码AV中文系列久久兔费
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-HBP1/BF488 Conjugated antibody (bs-15418R-BF488)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-15418R-BF488
英文名稱 Rabbit Anti-HBP1/BF488 Conjugated antibody
中文名稱 BF488標記的HMG盒區內含蛋白1抗體
別    名 FLJ16340; HBP 1; HBP1; HBP1_HUMAN; High mobility group box transcription factor 1; HMG box containing protein 1; HMG box transcription factor 1; HMG box-containing protein 1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 心血管  染色質和核信號  干細胞  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 58kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HBP1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
HBP1 is a member of the HMG family of transcription factors, which are characterized by the presence of a conserved protein motif, the high mobility group (HMG) 1 box, that mediates DNA binding. HBP-1 binds to the tumor suppressor proteins Rb and p130 and initiates cell cycle arrest.Terminal cell differentiation requires this initial cell cycle arrest followed by the coordinated expression of genes defined as tissue-specifc markers. Along with initiating the commitment to cell differentiation, the continued activity of HBP1 abrogates the expression of tissue-specific genes by associating with the MyoD proteins. In muscle cell differentiation, the MyoD family of transcription factors, which include Myf5, MyoD and myogenein, induce the expression of these cell-type specific proteins and contribute to the development of cell phenotypes. The progression of terminal differentiation is, therefore, dependent on both a decrease in HBP1 activity and the corresponding activation of MyoD-induced gene transcription.

Function:
Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

Subunit:
Binds the second PAH repeat of SIN3A (By similarity). Binds TCF4 and RB1.

Subcellular Location:
Nucleus.

Similarity:
Contains 1 AXH domain.
Contains 1 HMG box DNA-binding domain.

Database links:

Entrez Gene: 26959 Human

Entrez Gene: 73389 Mouse

Entrez Gene: 27080 Rat

SwissProt: O60381 Human

SwissProt: Q8R316 Mouse

SwissProt: Q62661 Rat

Unigene: 162032 Human

Unigene: 390461 Mouse

Unigene: 458534 Mouse

Unigene: 89226 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 国产一乱一伦一情 | 最近的2019中文字幕免费 | 国产免费丝袜调教视频 | 一区二区免费在线观看视频 | 亚洲欧美小说图片 | 日韩一区二区三区福利视频 | 日本黄色一级带 | 亚洲免费视频中文字幕 | 国产亚洲精品久久久一区 | 免费又黄又爽又猛大片午夜 | 久操国产精品 | 奇米首页777 | 中文字幕色偷偷人妻久久 | 成人av免费观看 | 中文无码亚洲精品字幕 | 成人免费看吃奶视频网站 | 国产a级淫片 | av高清在线观看 | 亚洲第一成人久久网站 | 91中文字幕视频 | 国产又爽又黄又爽又刺激 | 欧美性猛交久久久乱大交小说 | 一级毛片色一级 | 麻豆视频观看免费视频观看 | 国产精品综合久久久精品综合蜜臀 | 亚洲男人的天堂在线aⅴ视频 | a级片毛片| 国产精品午夜无码A体验区 国产精品无码AV不卡 | 九月婷婷 | 牲高潮99爽久久久久777 | 欧美色就插 | 免费黄色成年网站 | 香蕉视频官网 | 97SE亚洲国产综合自在线 | 91精品国产色综合久久不卡蜜臀 | 国产三级午夜理伦三级最新章节 | 亚洲精品自拍 | 久久久久久久久888 久久国产a级久久美女毛片 | 国产日产免费高清欧美一区 | 91在线观看视频 | 欧洲成人午夜精品无码区久久 |