97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
欧美激情一区二区三区在线视频,免费在线观看污网站,91部免费
Rabbit Anti-IFI30/FITC Conjugated antibody (bs-13591R-FITC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-13591R-FITC
英文名稱 Rabbit Anti-IFI30/FITC Conjugated antibody
中文名稱 FITC標(biāo)記的γ干擾素誘導(dǎo)蛋白IP30抗體
別    名 Gamma interferon inducible lysosomal thiol reductase; Gamma interferon inducible protein IP 30; GILT; IFI 30; interferon gamma inducible protein 30; Interferon gamma inducible protein 30 preproprotein; IP30; Lysosomal thiol reductase; Lysosomal thiol reductase, gamma-interferon-inducible; GILT_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  細(xì)胞類型標(biāo)志物  淋巴細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IFI30/GILT
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Proteins internalized into the endocytic pathway are usually degraded. Efficient proteolysis requires denaturation, induced by acidic conditions within lysosomes, and reduction of inter- and intrachain disulfide bonds. Cytosolic reduction is mediated enzymatically by thioredoxin. In the endocytic pathway, reduction of protein disulfide bonds is important for the generation of MHC class II-peptide complexes. This process is catalyzed by a gamma-interferon-inducible thiol reductase (GILT). GILT is synthesized as a precursor, and following delivery to MHC class II-containing compartments (MIICs), is processed to the mature form via cleavage of amino- and carboxy-terminal propeptides. A lysosomal thiol reductase, GILT, is optimally active at low pH and capable of catalyzing disulfide bond reduction both in vivo and in vitro. GILT is expressed constitutively in antigen-presenting cells and is induced by g-interferon in other cell types, suggesting a potentially important role in antigen processing. Additionally, T cell recognition of select exogenous and endogenous epitopes is dependent on tumor cell expression of GILT. The absence of GILT in melanomas alters antigen processing and the hierarchy of immunodominant epitope presentation.

Function:
The protein encoded by the IFI30 gene is a lysosomal thiol reductase which at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen presenting cells and induced by gamma interferon in other cell types. This enzyme has an important role in MHC class II restricted antigen processing.

Subcellular Location:
Lysosome.

Similarity:
Belongs to the GILT family.

Database links:

Entrez Gene: 10437 Human

Omim: 604664 Human

SwissProt: P13284 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 亚洲中文字幕国产综合 | 一本之道高清无码视频 | 一区国产精品 | 新japanesehdxxxx乱| 人妻无码中文字幕永久有效视频 | 我和同学人妻熟妇的激情 | 男男无码GV片在线看 | 国产69精品久久99不卡免费版 | 两性色午夜视频免费播放 | 免费视频三区 | www一起操 | 精品国产乱码久久久久久密桃99 | 91中文字幕在线视频 | 一人之下2在线观看 | JIZZJIZZ少妇亚洲水多 | 91精品国产日韩一区二区三区 | 无码国产69精品久久久久 | 免费日韩在线视频 | 无码少妇人妻专区在线视频 | 欧洲视频一区 | 可以免费观看av毛片 | 国产粉嫩av| 年轻的朋友6韩剧免费 | 又大又硬又爽免费视频 | 操碰久久| 免费古装a级毛片无码 | 亚洲AV成人片色在线观看蜜桃 | 日视频一区| 国产精品自在线拍亚洲另类 | 极品少妇xxxx精品少妇 | 日韩精品欧美在线成人 | 午夜羞羞影院免费播放在线观看 | 热99在线视频 | 欧美人与动牲交片免费播放 | 熟妇人妻无乱码中文字幕真矢织江 | 给老师下药挺进她的身体 | 国产亚洲精品AA片在线不卡 | 中文字幕永久在线播放 | 久久精品国产第一区二区三区 | 麻豆网站在线播放 | 国产AV无码专区亚洲AV毛网站 |