97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
欧美性色欧美a在线图片,免费精品国自产拍在线播放,在线视频观看成人
Rabbit Anti-IFI30/PE-Cy3 Conjugated antibody (bs-13591R-PE-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-13591R-PE-Cy3
英文名稱 Rabbit Anti-IFI30/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標(biāo)記的γ干擾素誘導(dǎo)蛋白IP30抗體
別    名 Gamma interferon inducible lysosomal thiol reductase; Gamma interferon inducible protein IP 30; GILT; IFI 30; interferon gamma inducible protein 30; Interferon gamma inducible protein 30 preproprotein; IP30; Lysosomal thiol reductase; Lysosomal thiol reductase, gamma-interferon-inducible; GILT_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  細(xì)胞類型標(biāo)志物  淋巴細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IFI30/GILT
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Proteins internalized into the endocytic pathway are usually degraded. Efficient proteolysis requires denaturation, induced by acidic conditions within lysosomes, and reduction of inter- and intrachain disulfide bonds. Cytosolic reduction is mediated enzymatically by thioredoxin. In the endocytic pathway, reduction of protein disulfide bonds is important for the generation of MHC class II-peptide complexes. This process is catalyzed by a gamma-interferon-inducible thiol reductase (GILT). GILT is synthesized as a precursor, and following delivery to MHC class II-containing compartments (MIICs), is processed to the mature form via cleavage of amino- and carboxy-terminal propeptides. A lysosomal thiol reductase, GILT, is optimally active at low pH and capable of catalyzing disulfide bond reduction both in vivo and in vitro. GILT is expressed constitutively in antigen-presenting cells and is induced by g-interferon in other cell types, suggesting a potentially important role in antigen processing. Additionally, T cell recognition of select exogenous and endogenous epitopes is dependent on tumor cell expression of GILT. The absence of GILT in melanomas alters antigen processing and the hierarchy of immunodominant epitope presentation.

Function:
The protein encoded by the IFI30 gene is a lysosomal thiol reductase which at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen presenting cells and induced by gamma interferon in other cell types. This enzyme has an important role in MHC class II restricted antigen processing.

Subcellular Location:
Lysosome.

Similarity:
Belongs to the GILT family.

Database links:

Entrez Gene: 10437 Human

Omim: 604664 Human

SwissProt: P13284 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 日韩免费黄色片 | 久久人人爽人人爽人人爽 | 不卡av免费在线观看 | 欧美成人看片一区二区三区尤物 | 国产无套激情在线视频 | 久久大香国产成人AV | 日韩一区二区三区福利视频 | 国产精品无码专区网站 | 日韩av一区二区三区四区 | 国产www亚洲а∨天堂 | 一区二区精品视频 | 亚洲国产精品视频一区二区 | 高潮毛片免费观看 | 久久婷婷五月综合成人D啪 成人av视频在线观看 | 亚洲国产黄色 | 亚洲aⅴ久久精品 | 精品99免费视频 | 久久精品不卡一区二区 | 久久久久久久波多野结衣高潮 | 日本不卡免费高清视频在线 | 亚洲国产成人精品无码区在线观看 | 99视频在线精品免费观看2 | 久久99久 | 国产日韩欧美一区二区三区乱码 | 麻豆社区 | 久草精品在线观看 | 91社区在线观看 | 久久WWW成人看片免费不卡 | 亚洲精品无码AV中文字幕 | 久久久精品欧美 | 欧美大黑BBB | 亚洲超碰在线 | 国产成人综合亚洲AV第一页 | 青青青在线视频免费观看 | 亚洲国产日韩A在线播放 | 欧美日韩一级黄 | 一本加勒比波多野结衣高清 | 就去色播 | 91亚洲区| 毛片三区 | 啊灬啊灬啊灬快灬深高潮了 |