97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
最新国产在线,天操天天干,交换一乱一性一爱
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-IFI30/BF350 Conjugated antibody (bs-13591R-BF350)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13591R-BF350
英文名稱 Rabbit Anti-IFI30/BF350 Conjugated antibody
中文名稱 BF350標記的γ干擾素誘導蛋白IP30抗體
別    名 Gamma interferon inducible lysosomal thiol reductase; Gamma interferon inducible protein IP 30; GILT; IFI 30; interferon gamma inducible protein 30; Interferon gamma inducible protein 30 preproprotein; IP30; Lysosomal thiol reductase; Lysosomal thiol reductase, gamma-interferon-inducible; GILT_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  細胞類型標志物  淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IFI30/GILT
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Proteins internalized into the endocytic pathway are usually degraded. Efficient proteolysis requires denaturation, induced by acidic conditions within lysosomes, and reduction of inter- and intrachain disulfide bonds. Cytosolic reduction is mediated enzymatically by thioredoxin. In the endocytic pathway, reduction of protein disulfide bonds is important for the generation of MHC class II-peptide complexes. This process is catalyzed by a gamma-interferon-inducible thiol reductase (GILT). GILT is synthesized as a precursor, and following delivery to MHC class II-containing compartments (MIICs), is processed to the mature form via cleavage of amino- and carboxy-terminal propeptides. A lysosomal thiol reductase, GILT, is optimally active at low pH and capable of catalyzing disulfide bond reduction both in vivo and in vitro. GILT is expressed constitutively in antigen-presenting cells and is induced by g-interferon in other cell types, suggesting a potentially important role in antigen processing. Additionally, T cell recognition of select exogenous and endogenous epitopes is dependent on tumor cell expression of GILT. The absence of GILT in melanomas alters antigen processing and the hierarchy of immunodominant epitope presentation.

Function:
The protein encoded by the IFI30 gene is a lysosomal thiol reductase which at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen presenting cells and induced by gamma interferon in other cell types. This enzyme has an important role in MHC class II restricted antigen processing.

Subcellular Location:
Lysosome.

Similarity:
Belongs to the GILT family.

Database links:

Entrez Gene: 10437 Human

Omim: 604664 Human

SwissProt: P13284 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 伊人综合久久 | 色啪视频| 亚洲AV成人午夜一区二区 | yellow视频在线观看免费 | 久久a免费视频 | 国产黑色丝袜流白浆视频 | 女人和男人视频网站 | 国产69精品99久久久久久宅男 | 成人羞羞视频在线观看 | 无码人妻丰满熟妇区毛片 | 无码被窝影院午夜看片爽爽JK | 91丨九色丨黑人外教 | avtt久久 | 无码专区国产精品第一页 | 视频免费一区 | 久久国产亚洲精品 | 亚洲成人高清av | 日韩欧美大片在线观看 | 日韩激情无码一级毛片 | 国产精品乱码一区二区 | 天天av天天 | 91九色性视频 | 久久久网站 | 精品成人免费 | 日本a级在线播放 | 人人妻人人澡人人爽人人精品AV | 久久精品女人毛片国产 | 亚洲欧美视频播放 | 追你而来免费观看 | www480jcom四虎 | MM1313亚洲国产精品 | 欧美视频免费在线 | 国产毛多水多女人a片 | 日本免费在线视频观看 | 92精品国产自产在线观看481页 | 欧美做受又硬又粗又大视频 | 欧美日韩国产人妻无码 | 中文字幕久久波多野结衣AV | 国精产品一码一码三MBA | 亚洲日韩av无码一区二区三区人 | 凌晨三点免费视频www |