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Rabbit Anti-HINT1/BF647 Conjugated antibody (bs-10228R-BF647)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-10228R-BF647
英文名稱 Rabbit Anti-HINT1/BF647 Conjugated antibody
中文名稱 BF647標記的組氨酸三聚體核苷結合蛋白1抗體
別    名 histidine triad nucleotide binding protein 1; Adenosine 5' monophosphoramidase; Adenosine 5'-monophosphoramidase; HINT 1; HINT-1; histidine triad nucleotide binding protein 1; histidine triad nucleotide binding protein; histidine triad nucleotide-binding protein; Histidine triad nucleotide-binding protein 1; PKCI 1; PKCI-1; PKCI1; PRKCNH1; Protein kinase C inhibitor 1; Protein kinase C interacting protein 1; Protein kinase C-interacting protein 1; HINT1_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  免疫學  結合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 14kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HINT1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The protein encoded by this gene can hydrolyze substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif, which is part of the loop that binds to the substrate. This gene has been found to be a tumor suppressing gene. Several transcript variants, but only one of them protein-coding, have been found for this gene. [provided by RefSeq, Dec 2012].

Function:
Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2.

Subunit:
Homodimer. Interacts with CDK7.

Subcellular Location:
Cytoplasm. Nucleus. Note=Interaction with CDK7 leads to a more nuclear localization.

Tissue Specificity:
Widely expressed.

Similarity:
Belongs to the HINT family.
Contains 1 HIT domain.

Database links:

Entrez Gene: 3094 Human

Entrez Gene: 15254 Mouse

Entrez Gene: 690660 Rat

Omim: 601314 Human

SwissProt: P49773 Human

SwissProt: P70349 Mouse

SwissProt: P62959 Rat

Unigene: 483305 Human

Unigene: 425 Mouse

Unigene: 138667 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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