97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
91成品人网页进入入口,51啪影院,亚洲第一中文av
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-TRPV5/Gold Conjugated antibody (bs-8534R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-8534R-Gold
英文名稱 Rabbit Anti-TRPV5/Gold Conjugated antibody
中文名稱 膠體金標記的辣椒素受體5抗體
別    名 Calcium transport protein 2; Calcium transporter 2; CAT 2; CAT2; ECAC 1; ECaC; ECAC1; Epithelial calcium channel 1; Osm 9 like TRP channel 3; Osm-9-like TRP channel 3; OTRPC 3; OTRPC3; Transient receptor potential cation channel subfamily V member 5; TRPV 5; TrpV5; TRPV5_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  免疫學  神經生物學  轉錄調節因子  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 83kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRPV5
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
Transient receptor potential (TRP) proteins are cation-sensitive channels that modulate a myriad of cellular functions, including temperature sensation and vasoregulation Transcribed from a gene adjacent to VR-1, the thermal-sensitive, capsaicin-insensitive TRPV3 is expressed at warm temperatures; expression increases in response to noxious temperatures. Human TRPV3 is expressed in skin, tongue, dorsal root ganglion, trigeminal ganglion, spinal cord and brain. In addition, TRPV3 is co-expressed in dosal root ganglion neurons with VR-1. TRPV3 associates with VR-1 and may modulate VR-1 activity. The 729 amino acid TRPV5 (ECAC1) protein comprises six transmembrane domains, multiple potential phosphorylation sites, an N-linked glycosylation site and three ankyrin repeat regions. It is abundantly expressed in kidney, jejunum and pancreas, and at lower levels in testis, prostate, placenta, brain, colon and rectum. TRPV5 controls the rate-limiting step of vitamin D3-regulated Ca2+ reabsorption in kidney and intestine; the 5’-flanking region of TRPV5 contains four putative vitamin D3-responsive elements.

Function:
Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine. The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay. Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.

Subunit:
Homotetramer and probably heterotetramer with TRPV6. Interacts with TRPV6. Interacts with S100A10 and probably with the ANAX2-S100A10 heterotetramer. The interaction with S100A10 is required for the trafficking to the plasma membrane. Interacts with calmodulin. Interacts with BSPRY, which results in its inactivation (By similarity).

Subcellular Location:
Apical cell membrane. Colocalized with S100A10 and ANAX2 along the apical domain of kidney distal tubular cells (By similarity). The expression of the glycosylated form in the cell membrane is increased in the presence of WNK3.

Tissue Specificity:
Expressed at high levels in kidney, small intestine and pancreas, and at lower levels in testis, prostate, placenta, brain, colon and rectum.

Post-translational modifications:
Glycosylated.

Similarity:
Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV5 sub-subfamily.
Contains 5 ANK repeats.

Database links:

Entrez Gene: 56302 Human

Entrez Gene: 194352 Mouse

Entrez Gene: 116469 Rat

Omim: 606679 Human

SwissProt: Q9NQA5 Human

SwissProt: P69744 Mouse

SwissProt: Q9JIP0 Rat

Unigene: 283369 Human

Unigene: 135734 Mouse

Unigene: 137513 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 国产最顶级的黄色片在线免费观看 | 国产午夜精品久久久久久免费视 | 中文国产三级 | 91国产一区 | 亚洲韩国一区二区三区 | 1717she国产精品高清在线观看 | 四虎影视库www111we | 熟女人妻aⅴ一区二区三区60路 | 欧美性猛交XXXX黑人猛交 | 亚洲高清免费观看在线视频 | 蜜臀av免费一区二区三区久久乐 | 黄色视频a级毛片 | 性屋娱乐wwwsex5me | 国产一级片内射视频 | 熟妇人妻无乱码中文字幕 | 色综合久久天天综合网 | 日韩福利二区 | a免费在线观看 | JIZZJIZZ少妇亚洲水多 | 国产成人精品日本亚洲一区 | 国内精品国内自产视频 | ipx亚洲一区二区三区 | 中文字幕免费一区二区 | 欧美精欧美乱码一二三四区 | 成人天堂网| 亚洲美女久久 | 日本少妇激三级做爰在线 | 中午字幕无线码一区2020 | 成年人中文字幕在线观看 | 精品亚洲一区二区三区在线观看 | 欧美黑人粗暴多交高潮水最多 | 亚洲精品国产精品乱码不卞 | 亚洲色成人一区二区三区 | 国产亚洲精品A在线看 | 人妻无码AV一区二区三区精品 | 噜噜噜av在线观看 | 日本一区二区免费高清视频 | 无码人妻精品一区二区三区久久 | 国产精品免费视频二三区 | 成人女人免费毛片 | 一区二区三区四区五区中文字幕 |