97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質(zhì)量反饋  關于我們  聯(lián)系我們
免费看男女www网站入口在线,91嫩草在线免费观看,凌晨三点免费视频www
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-PIK3AP1/APC Conjugated antibody (bs-13675R-APC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-13675R-APC
英文名稱 Rabbit Anti-PIK3AP1/APC Conjugated antibody
中文名稱 APC標記的磷酸肌醇3激酶接頭蛋白1抗體
別    名 B cell adaptor protein; B-cell adapter for phosphoinositide 3-kinase; B-cell phosphoinositide 3-kinase adapter protein 1; BCAP; BCAP_HUMAN; OTTHUMP00000020175; OTTHUMP00000020176; Phosphoinositide 3 kinase adaptor protein 1; Phosphoinositide 3-kinase adapter protein 1; PIK3AP1; RP11-34E5.3.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉(zhuǎn)導  激酶和磷酸酶  細胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 90kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PIK3AP1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
B cell adaptor for phosphoinositide 3-kinase (BCAP) is a tyrosine kinase substrate that bridges B cell receptor (BCR) associated kinases to the PIK3 pathway. Syk, Btk or Lyn-dependent tyrosine phosphorylation of BCAP, provides binding sites for the p85 subunit of PIK3. BCAP mRNA is present in mouse spleen, thymus, liver, lung, macrophage and B cell lines. Human BCAP maps to chromosome 10q24.2.

Function:
Involved in the activation of phosphoinositide 3-kinase (PI3K) in B-cells and in natural killer (NK) cells. Couples B-cell antigen receptor (BCR) to PI3K activation by providing a docking site for the PI3K subunit PIK3R1, which contributes to B-cell development. Seems to have a complementary role with CD19 in PI3K activation (By similarity). May be involved in the survival of mature B cells via activation of REL.

Subunit:
Homooligomer (By similarity). Interacts (phosphorylated on tyrosine residues within YXXM motifs) with PIK3R1 (via SH2 domain); required for BCR- and TLR-mediated activation of phosphoinositide 3-kinase. Interacts (via polyproline C-terminal region) with ABI1 (via SH3 domain); the interaction promotes phosphorylation of PIK3AP1 by ABL1. May interact with MYD88 and TIRAP (By similarity).

Subcellular Location:
Cytoplasm. Cell membrane.

Tissue Specificity:
Expressed in natural killer (NK) cells.

Post-translational modifications:
Phosphorylated on tyrosine residues within the YXXM motifs by BTK and SYK (By similarity). Isoform 1 and isoform 2 are phosphorylated on tyrosine residues, most likely within the YXXM motifs, via CD19 activation (By similarity).
Phosphorylated on tyrosine residues in C-terminus region by ABL1 and V-abl.

Similarity:
Contains 1 DBB domain.

Database links:

Entrez Gene: 118788 Human

Entrez Gene: 83490 Mouse

Omim: 607942 Human

SwissProt: Q6ZUJ8 Human

SwissProt: Q9EQ32 Mouse

Unigene: 310456 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 真人二十三式性视频(动) | 色噜噜狠狠色综合网图区 | 日本一区二区高清不卡 | 亚洲综合色丁香婷婷六月图片 | 国产在线精品一区二区三区 | 亚洲成人动漫网站 | 国产精品538一区二区在线 | 色窝窝色蝌蚪在线视频 | 国产又粗又黄又爽又硬的软件 | 少妇对白露脸打电话系列 | 皇色在线视频 | 久久伊人天堂 | 欧美黑人肉体狂欢大派对 | 国产综合久久一区二区三区 | 国产成人久久综合777777麻豆 | 电家庭影院午夜 | 97超碰在线视 | 国产成网站18禁止久久影院 | 東热精品中字久久无码五月天 | 日本高清视频在线观看 | 深夜免费观看视频 | 日本黄色录像视频 | 蜜臀av免费一区二区三区水牛 | 爆乳喷奶水无码正在播放 | 中文字幕久久波多野结衣AV | 99精品不卡一区二区三区 | 91免费网 | 日本一区免费看 | 国产精品原创巨作av | 日本免费高清 | 在线一区二区三区精品 | 国内精品国产成人国产三级李采潭 | 国产色视频在线播放 | 中文字幕亚洲色妞精品天堂 | 可以免费看的av毛片 | 亚洲成av人在线看 | 精品一区二区三区视频日产 | 国产成人久久久精品二区三区 | 一级毛片免费网站 | 夜夜操天天干 | 动漫91 |