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Rabbit Anti-PCDH10/Cy3 Conjugated antibody (bs-13723R-Cy3)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13723R-Cy3
英文名稱 Rabbit Anti-PCDH10/Cy3 Conjugated antibody
中文名稱 Cy3標記的原鈣粘附蛋白10抗體
別    名 DKFZp761O2023; KIAA1400; MGC133344; OL PCDH; Ortholog of OL pcdh; OTTHUMP00000220001; PCD10_HUMAN; PCDH10; PCDH19; Protocadherin 10; Protocadherin-10.  
Journal
PMID
IF
Application
[IF=4.5] Deng, Jingyu, et al. "Clinical Significance of the Methylated Cytosine-Phosphate-Guanine Sites of Protocadherin-10 Promoter for Evaluating the Prognosis of Gastric Cancer." Journal of the American College of Surgeons (2014).  WB ;  Human.  
[IF=3.989] Jinsong He. et al. Low Expression of ZNF154 is Related to Poor Prognosis in Gastric Cancer. Cancer Manag Res. 2022; 14: 659–672  IHC ;  Human.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  神經生物學  信號轉導  細胞粘附分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Pig, Cow, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 110kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PCDH10
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDH10 (protocadherin 10), also known as PCDH19 or OL-PCDH, is a 1,040 amino acid single-pass type I membrane protein that contains six cadherin domains and one transmembrane domain. Expressed at moderate levels in brain, ovary and testis and present at lower levels in all other tissues, PCDH10 functions as a calcium-dependent cell-adhesion protein that may function as a tumor suppressor. When underexpressed, PCDH10 is associated with the progression of various carcinomas, including gastric cancer.

Function:
Potential calcium-dependent cell-adhesion protein.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Moderately expressed in all regions of the brain examined, as well as in testis and ovary, and low expression in all other tissues tested.

Similarity:
Contains 6 cadherin domains.

Database links:

Entrez Gene: 57575 Human

Entrez Gene: 531875 Cow

Entrez Gene: 18526 Mouse

Omim: 608286 Human

SwissProt: Q9P2E7 Human

Unigene: 192859 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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