97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
精品国产高清自在线一区二区,欧美午夜aaaaaa免费视频,能在线观看的av网站
Rabbit Anti-JIP2/Cy5 Conjugated antibody (bs-13647R-Cy5)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-13647R-Cy5
英文名稱 Rabbit Anti-JIP2/Cy5 Conjugated antibody
中文名稱 Cy5標(biāo)記的絲裂原活化蛋白激酶相互作用蛋白2抗體
別    名 MAPK8IP2; C jun amino terminal kinase interacting protein 2; C-jun-amino-terminal kinase-interacting protein 2; Homologous to mouse JIP 1; IB 2; IB-2; IB2; Islet brain 2; Islet-brain-2; JIP 2; JIP-2; JIP2; JIP2_HUMAN; JNK interacting protein 2; JNK MAP kinase scaffold protein 2; JNK MAP kinase scaffold protein JIP2; JNK-interacting protein 2; MAPK8IP2; Mitogen activated protein kinase 8 interacting protein 2; Mitogen-activated protein kinase 8-interacting protein 2; PRKM8 interacting protein like; PRKM8IPL.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Cow, Horse, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 88kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human JIP2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
c-Jun NH2-terminal kinases (JNKs) are distant members of the MAP kinase family (1). JNK1 is activated by dual phosphorylation at a Thr-Pro-Tyr motif in response to ultraviolet (UV) light, and it functions to phosphorylate c-Jun at amino terminal serine regulatory sites, Ser-63 and Ser-73, resulting in transcriptional activation (2-5). Two additional JNK family members have been identified as JNK2 and JNK3 (3). JIP-1 (for JNK interacting protein-1) has been identified as a cytoplasmic inhibitor of JNK that retains JNK in the cytoplasm, thereby inhibiting JNK-regulated gene expression. Evidence suggests that JNK1 and JNK2 bind to JIP-1 with greater affinity than to ATF-2 and c-Jun, which are targets of the JNK signaling pathway. JIP-1 contains an amino terminal JNK binding domain and a carboxy terminal SH3 domain. ATF-2 and c-Jun also contain the JNK binding domain and are thought to compete with JIP-1 for JNK binding (6). Multiple splice variants if JIP-1, including JIP-1b, JIP-1c (also designated islet-brain 1 or IB-1), JIP-2a, JIP-2b and JIP-3, have been identified in brain (7).

Function:
The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP2 inhibits IL1 beta-induced apoptosis in insulin-secreting cells. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins.

Subcellular Location:
Cytoplasm. Accumulates in cell surface projections.

Tissue Specificity:
Expressed mainly in the brain and pancreas, including insulin-secreting cells. In the nervous system, more abundantly expressed in the cerebellum, pituitary gland, occipital lobe and the amygdala. Also expressed in fetal brain. Very low levels found in uterus, ovary, prostate, colon, testis, adrenal gland, thyroid gland and salivary gland.

Similarity:
Belongs to the JIP scaffold family.
Contains 1 PID domain.
Contains 1 SH3 domain.

Database links:
  • Entrez Gene: 23542 Human
  • Entrez Gene: 60597 Mouse

    Entrez Gene: 315220 Rat

    Omim: 607755 Human

    SwissProt: Q13387 Human

    SwissProt: Q9ERE9 Mouse

    Unigene: 558180 Human

    Unigene: 173337 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
    通過國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
    通過國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
    京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
    主站蜘蛛池模板: 卡一卡二卡三免费视频 | 97影院网 | 91精品视频网 | 亚洲永久经典 | 少妇毛又多又黑又大又粗 | 正在播放长泽梓免费观看 | 东京复仇者第三季天竺篇在线观看 | 操操网址| 在线观看免费观看av | 91麻豆免费版 | 欧美激情黑白配 | 免费无码成人AV片在线在线播放 | 欧美精品一区二区久久久 | 欧美日韩亚洲中文字幕一区二区三区 | 国产成熟人妻换╳╳╳╳ | 欧美巨大另类极品videosbest | 妺妺窝人体色777777 | 无码一区二区三区不卡AV | 欧美群交射精内射颜射潮喷 | 一级做a爰片久久毛片一 | 大胆av| ts国产人妖视频在线观看 | 日本伦理在线视频 | 蜜臀av免费一区二区三区久久乐 | 免费人成又黄又爽又色 | 青青草视频4 | 久久97超碰 | 床震吃胸膜奶免费视频 | 欧美一区自拍 | 九九热精品视频在线免费观看 | 亚洲日韩一区精品射精 | 二次元人物桶二次元人物免费 | 麻豆手机在线观看 | 成人手机在线视频 | 国产成人一区二区在线观看 | 67194中文字幕在线观看日韩 | 日韩av高清在线 | 亚洲日韩av片在线观看 | 特级全黄男女交高清视频在线观看 | 四虎影视最新网站 | 在线A亚洲老鸭窝天堂AV高清 |