97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號(hào)           掃碼咨詢(xún)技術(shù)支持           掃碼咨詢(xún)技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
www.av色,久久国产视频精品,久久五十路丰满熟女中出
Rabbit Anti-JIP2/Cy7 Conjugated antibody (bs-13647R-Cy7)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-13647R-Cy7
英文名稱(chēng) Rabbit Anti-JIP2/Cy7 Conjugated antibody
中文名稱(chēng) Cy7標(biāo)記的絲裂原活化蛋白激酶相互作用蛋白2抗體
別    名 MAPK8IP2; C jun amino terminal kinase interacting protein 2; C-jun-amino-terminal kinase-interacting protein 2; Homologous to mouse JIP 1; IB 2; IB-2; IB2; Islet brain 2; Islet-brain-2; JIP 2; JIP-2; JIP2; JIP2_HUMAN; JNK interacting protein 2; JNK MAP kinase scaffold protein 2; JNK MAP kinase scaffold protein JIP2; JNK-interacting protein 2; MAPK8IP2; Mitogen activated protein kinase 8 interacting protein 2; Mitogen-activated protein kinase 8-interacting protein 2; PRKM8 interacting protein like; PRKM8IPL.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  激酶和磷酸酶  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Cow, Horse, )
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 88kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human JIP2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
c-Jun NH2-terminal kinases (JNKs) are distant members of the MAP kinase family (1). JNK1 is activated by dual phosphorylation at a Thr-Pro-Tyr motif in response to ultraviolet (UV) light, and it functions to phosphorylate c-Jun at amino terminal serine regulatory sites, Ser-63 and Ser-73, resulting in transcriptional activation (2-5). Two additional JNK family members have been identified as JNK2 and JNK3 (3). JIP-1 (for JNK interacting protein-1) has been identified as a cytoplasmic inhibitor of JNK that retains JNK in the cytoplasm, thereby inhibiting JNK-regulated gene expression. Evidence suggests that JNK1 and JNK2 bind to JIP-1 with greater affinity than to ATF-2 and c-Jun, which are targets of the JNK signaling pathway. JIP-1 contains an amino terminal JNK binding domain and a carboxy terminal SH3 domain. ATF-2 and c-Jun also contain the JNK binding domain and are thought to compete with JIP-1 for JNK binding (6). Multiple splice variants if JIP-1, including JIP-1b, JIP-1c (also designated islet-brain 1 or IB-1), JIP-2a, JIP-2b and JIP-3, have been identified in brain (7).

Function:
The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP2 inhibits IL1 beta-induced apoptosis in insulin-secreting cells. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins.

Subcellular Location:
Cytoplasm. Accumulates in cell surface projections.

Tissue Specificity:
Expressed mainly in the brain and pancreas, including insulin-secreting cells. In the nervous system, more abundantly expressed in the cerebellum, pituitary gland, occipital lobe and the amygdala. Also expressed in fetal brain. Very low levels found in uterus, ovary, prostate, colon, testis, adrenal gland, thyroid gland and salivary gland.

Similarity:
Belongs to the JIP scaffold family.
Contains 1 PID domain.
Contains 1 SH3 domain.

Database links:
  • Entrez Gene: 23542 Human
  • Entrez Gene: 60597 Mouse

    Entrez Gene: 315220 Rat

    Omim: 607755 Human

    SwissProt: Q13387 Human

    SwissProt: Q9ERE9 Mouse

    Unigene: 558180 Human

    Unigene: 173337 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
    通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
    通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
    京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
    主站蜘蛛池模板: 强行肉体进入hdxxxx办公室 | 久久久精品动漫 | 亚洲理论中文字幕 | 色影天堂 | 4399午夜理伦免费播放大全 | 一级做性色a爱片久久毛片欧 | 欧美高清一区三区在线专区 | 人人99精 | 亚洲第一黄色网址 | 四虎影视库www111we | 国产手机在线αⅴ片无码观看 | 日本大片在线免费观看 | 欧美高清一区三区在线专区 | 亚洲人成网站在线观看妞妞网 | 苍井空亚洲精品AA片在线播放 | 女人下边被添全过程A片图片 | 狼人无码中文在线观看 | 一级黄色录像影片夫妻性生活影片 | 在线亚洲无砖砖区免费 | 激情综合色综合啪啪五月丁香搜索 | 亚洲精品中文字幕乱码4区 一本一道波多野结衣av黑人 | 四虎影视最新网站 | 小小影视网在线观看 | 亚洲午夜无码久久yy6080 | 狠狠五月| 99热99热99 | 婷婷影院在线综合免费视频 | 欧美猛交xxx | 国产在线xxxx| 国产三级网站 | 日韩黄色一级片 | 国产日韩欧美一区二区 | 日本三级吃奶头添泬 | 国产A级毛片色咪味 | av蜜臀| 精品国产一区二区三区麻豆小说 | 丰满少妇被猛烈进出69影院 | 久久男女| 亚洲国产成人爱av在线播放 | 天天久久久 | 午夜影院在线午夜影院在线观看 |