97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
亚洲区精品3d国漫同人,亚洲国产精品一,国产a网站
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-JIP2/PE Conjugated antibody (bs-13647R-PE)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13647R-PE
英文名稱 Rabbit Anti-JIP2/PE Conjugated antibody
中文名稱 PE標記的絲裂原活化蛋白激酶相互作用蛋白2抗體
別    名 MAPK8IP2; C jun amino terminal kinase interacting protein 2; C-jun-amino-terminal kinase-interacting protein 2; Homologous to mouse JIP 1; IB 2; IB-2; IB2; Islet brain 2; Islet-brain-2; JIP 2; JIP-2; JIP2; JIP2_HUMAN; JNK interacting protein 2; JNK MAP kinase scaffold protein 2; JNK MAP kinase scaffold protein JIP2; JNK-interacting protein 2; MAPK8IP2; Mitogen activated protein kinase 8 interacting protein 2; Mitogen-activated protein kinase 8-interacting protein 2; PRKM8 interacting protein like; PRKM8IPL.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  信號轉導  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Cow, Horse, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 88kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human JIP2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
c-Jun NH2-terminal kinases (JNKs) are distant members of the MAP kinase family (1). JNK1 is activated by dual phosphorylation at a Thr-Pro-Tyr motif in response to ultraviolet (UV) light, and it functions to phosphorylate c-Jun at amino terminal serine regulatory sites, Ser-63 and Ser-73, resulting in transcriptional activation (2-5). Two additional JNK family members have been identified as JNK2 and JNK3 (3). JIP-1 (for JNK interacting protein-1) has been identified as a cytoplasmic inhibitor of JNK that retains JNK in the cytoplasm, thereby inhibiting JNK-regulated gene expression. Evidence suggests that JNK1 and JNK2 bind to JIP-1 with greater affinity than to ATF-2 and c-Jun, which are targets of the JNK signaling pathway. JIP-1 contains an amino terminal JNK binding domain and a carboxy terminal SH3 domain. ATF-2 and c-Jun also contain the JNK binding domain and are thought to compete with JIP-1 for JNK binding (6). Multiple splice variants if JIP-1, including JIP-1b, JIP-1c (also designated islet-brain 1 or IB-1), JIP-2a, JIP-2b and JIP-3, have been identified in brain (7).

Function:
The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP2 inhibits IL1 beta-induced apoptosis in insulin-secreting cells. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins.

Subcellular Location:
Cytoplasm. Accumulates in cell surface projections.

Tissue Specificity:
Expressed mainly in the brain and pancreas, including insulin-secreting cells. In the nervous system, more abundantly expressed in the cerebellum, pituitary gland, occipital lobe and the amygdala. Also expressed in fetal brain. Very low levels found in uterus, ovary, prostate, colon, testis, adrenal gland, thyroid gland and salivary gland.

Similarity:
Belongs to the JIP scaffold family.
Contains 1 PID domain.
Contains 1 SH3 domain.

Database links:
  • Entrez Gene: 23542 Human
  • Entrez Gene: 60597 Mouse

    Entrez Gene: 315220 Rat

    Omim: 607755 Human

    SwissProt: Q13387 Human

    SwissProt: Q9ERE9 Mouse

    Unigene: 558180 Human

    Unigene: 173337 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
    通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
    通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
    京ICP備05066980號-1         京公網安備110107000727號
    主站蜘蛛池模板: 精品久久久久久无码人妻A片 | 岛国av在线免费观看 | 日本a人精品 | 伊人久久综合一区二区 | 精品久久久久久 | 成人免费视频国一国二在线观看 | 久久久久久久久毛片精品火炮 | 夜夜狠狠干 | 无码国内精品人妻少妇蜜桃视频 | 国产欧美一区二区精品仙草咪 | 国产亚洲精品欧洲在线观看 | 久久看精品 | 欧美黄色一级片在线观看 | 国产九色视频在线观看 | 国产裸拍裸体视频在线观看 | 天天舔夜夜 | 黑人精品欧美一区二区蜜桃 | 1024久久| 精品国产一区二区三区久久狼5月 | 九色国产精品入口 | 国产AV无码专区亚洲精品 | 亚洲国产婷婷香蕉久久久久久99 | 狠狠躁躁夜夜躁波多野结依 | 欧美片网站免费 | 老年人一级黄色片 | 综合久久国产 | 成人亚洲精品久久99狠狠 | 日本大黄视频 | 福利丝袜美腿视频网站 | 男女啪啪做爰高潮无遮挡 | 艳妇荡乳豪妇荡乳av精东 | 久久天天躁狠狠躁夜夜96流白浆 | 欧美成人自拍 | 另类综合日韩欧美亚洲 | 亚洲午夜福利在线观看老司机 | 天天做天天爱夜夜爽女人爽 | 香蕉视频官网 | 日本少妇做爰全过程二区 | 亚洲丝袜第一页 | 麻豆成人免费视频 | xxxxx非洲黑人猛内射 |