97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
日韩黄色小视频,亚洲精品国产二区,久久精品国产99国产精2021
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-ER81/Cy3 Conjugated antibody (bs-10949R-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-10949R-Cy3
英文名稱 Rabbit Anti-ER81/Cy3 Conjugated antibody
中文名稱 Cy3標記的轉錄因子ER81蛋白抗體
別    名 DKFZp781L0674; ER81; ER81 protein; ETS translocation variant 1; ets variant gene 1; Ets-related protein 81; Etsrp81; ETV 1; ETV1; ETV1_HUMAN; MGC104699; MGC120533; MGC120534.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  干細胞  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 55kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ER81
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element. All of the Ets proteins recognize the same central core sequence but each protein interacts with unique sequences that flank this core. PEA3 binds the motif 5'-AGGAAG-3', while ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3'. PEA3 is expressed at readily detectable levels in cells of epithelial and fibroblastic origin. Unlike other members of the Ets family, including Ets-1 and Ets-2, PEA3 is not expressed in hematopoietic cells. ER81 is highly expressed in brain, testis, lung and heart. ER81 is also moderately expressed in spleen, pancreas, colon and small intestine. During development, ER81, PEA3 and ERM display unique expression patterns which suggest these transcriptional factors play an important role in organogenesis. ERK-1 activates ER81 transcriptional activity, while MAPKAP kinase 2 inhibits ER81.

Function:
Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.

Subcellular Location:
Nucleus.

Tissue Specificity:
Very highly expressed in brain, highly expressed in testis, lung and heart, moderately in spleen, small intestine, pancreas and colon, weakly in liver, prostate and thymus, very weakly in skeletal muscle, kidney and ovary and not in placenta and peripheral blood leukocytes.

Post-translational modifications:
Sumoylated.

DISEASE:
Defects in ETV1 are a cause of Ewing sarcoma (ES) [MIM:612219]. A highly malignant, metastatic, primitive small round cell tumor of bone and soft tissue that affects children and adolescents. It belongs to the Ewing sarcoma family of tumors, a group of morphologically heterogeneous neoplasms that share the same cytogenetic features. They are considered neural tumors derived from cells of the neural crest. Ewing sarcoma represents the less differentiated form of the tumors. Note=A chromosomal aberration involving ETV1 is found in patients with Erwing sarcoma. Translocation t(7;22)(p22;q12) with EWSR1.

Similarity:
Belongs to the ETS family.
Contains 1 ETS DNA-binding domain.

Database links:

Entrez Gene: 395748 Chicken

Entrez Gene: 540846 Cow

Entrez Gene: 475246 Dog

Entrez Gene: 2115 Human

Entrez Gene: 14009 Mouse

Entrez Gene: 362733 Rat

Omim: 600541 Human

SwissProt: Q2KIC2 Cow

SwissProt: P50549 Human

SwissProt: P41164 Mouse

Unigene: 22634 Human

Unigene: 4866 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 精品国产乱码久久久久久密桃99 | 国产SUV精品一区二区33 | 东京一本到熟无码免费视频 | aⅴ小次郎改为av小四郎 | 韩国毛片在线 | 婷婷成人丁香五月综合激情 | 日本一二不卡 | 性饥渴少妇AV无码毛片 | 日日噜噜大屁股熟妇 | 国产一片姪乱洗澡 | 成人一级视频 | 日韩欧美精品一区二区三区经典 | www.九九视频 | 九九欧美 | 久久久二 | 国产午夜亚洲精品 | 大地资源在线观看免费高清官网 | 国产精品91xxx | 国产一区久久 | 久久久久亚洲AV成人片无码 | 18国产精品福利片久久婷 | 免费黄网在线 | 日韩黄色在线播放 | 国产精品18久久久久久久网站 | 成年免费大片黄在线观看一级 | va久久久久精码专区 | 精品91在线视频 | 囯产精品一品二区三区 | 中文字幕免费亚洲 | 在线视频你懂 | 国产视频精品xxxx | 四虎影视在线观看2413 | 少妇一级淫片 | 91精品综合久久久久m3u8 | 中出乱码av亚洲精品久久天堂 | 精品乱码一区二区三四区视频 | 99久在线 | 亚洲情XO亚洲色XO无码 | 少妇撒尿一区二区在线视频 | 91天天爽 | 亚洲国产婷婷香蕉久久久久久99 |