97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
传媒天美果冻AAAAA,国产区在线观看视频,www国产在线观看
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-phospho-eIF4EBP1(Thr70)/Gold Conjugated antibody (bs-14550R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-14550R-Gold
英文名稱 Rabbit Anti-phospho-eIF4EBP1(Thr70)/Gold Conjugated antibody
中文名稱 膠體金標記的磷酸化eIF4E結合蛋白抗體
別    名 eIF4EBP1 (phospho T70); eIF4EBP1 (phospho Thr70); p-eIF4EBP1 (Thr70); eIF4EBP1; Eukaryotic translation initiation factor 4E binding protein 1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E BP1; 4EBP1; BP 1; BP1; eIF4E binding protein 1; eIF4E-binding protein 1; Eukaryotic translation initiation factor 4E binding protein 1; MGC4316; PHAS I; PHASI; PHAS-I; PHAS; 4E-BP1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; Phosphorylated heat and acid stable protein regulated by insulin 1; 4EBP1_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
產品類型 磷酸化抗體 
研究領域 細胞生物  轉運蛋白  新陳代謝  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat,  (predicted: Human, Mouse, Chicken, Dog, Cow, Horse, Sheep, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 12kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human EIF4B around the phosphorylation site of Thr70
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008].

Function:
Regulates eIF4E activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.

Subunit:
Hypophosphorylated EIF4EBP1 competes with EIF4G1/EIF4G3 to interact with EIF4E; insulin stimulated MAP-kinase (MAPK1 and MAPK3) or mTORC1 phosphorylation of EIF4EBP1 causes dissociation of the complex allowing EIF4G1/EIF4G3 to bind and consequent initiation of translation. Interacts with RPTOR.

Post-translational modifications:
Phosphorylated on serine and threonine residues in response to insulin, EGF and PDGF. Phosphorylation at Thr-37, Thr-46, Ser-65 and Thr-70 is regulated by mTORC1. Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the eIF4E-binding protein family.

Database links:

Entrez Gene: 1978 Human

Entrez Gene: 13685 Mouse

Entrez Gene: 116636 Rat

Omim: 602223 Human

SwissProt: Q13541 Human

SwissProt: Q60876 Mouse

SwissProt: Q62622 Rat

Unigene: 411641 Human

Unigene: 6700 Mouse

Unigene: 11161 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 一区二区三区波多野结衣在线观看 | 啊灬啊灬啊灬快灬高潮了听书 | 日本人在线观看 | 欧美孕妇变态重口另类 | 一区二区观看 | 在线观看视频色潮 | 精品国产一区二区三区久久狼5月 | 99久久免费看精品国产一区 | 91精品国产色综合久久不卡98最新章节 | 在线视频1区 | 99精品一级欧美片免费播放资讯 | 亚洲精品无码精品MV在线观看 | 无限看片的视频高清在线 | 中文字幕一区在线观看视频 | 九九久久精品一区 | 日韩午夜高清 | 亚洲性高清SUV| 亚洲最大天堂无码精品区 | 99999色| 亚洲欧美日韩另类精品一区 | 精品久久久国产 | 亚洲国产成人精品女人久久久久 | 国产视频精品自拍 | 国产精品久久久亚洲 | 国产精品午夜一区二区欲梦 | 粗大猛烈进出呻吟声视频 | 久久热这里只有精品在线观看 | 色淫影院 | 久久综合影院 | 中文字幕在线视频精品 | 又硬又粗又大一区二区三区视频 | 成人网免费 | 日本一区二区免费在线观看 | 亚洲欧美综合久久久久久 | 国产在线视频福利 | 激情另类小说区图片区视频区 | 日本69视频 | 久久网站av | 91久久人澡人人添人人爽欧美 | 欧美日韩一区二区三区不卡 | 高清无码免费视频专区 |