97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
亚洲视频手机在线,毛片av片,日韩在线一二三四区第一页
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-phospho-eIF4EBP1(Thr70)/PE-Cy3 Conjugated antibody (bs-14550R-PE-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-14550R-PE-Cy3
英文名稱 Rabbit Anti-phospho-eIF4EBP1(Thr70)/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標記的磷酸化eIF4E結合蛋白抗體
別    名 eIF4EBP1 (phospho T70); eIF4EBP1 (phospho Thr70); p-eIF4EBP1 (Thr70); eIF4EBP1; Eukaryotic translation initiation factor 4E binding protein 1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E BP1; 4EBP1; BP 1; BP1; eIF4E binding protein 1; eIF4E-binding protein 1; Eukaryotic translation initiation factor 4E binding protein 1; MGC4316; PHAS I; PHASI; PHAS-I; PHAS; 4E-BP1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; Phosphorylated heat and acid stable protein regulated by insulin 1; 4EBP1_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產品類型 磷酸化抗體 
研究領域 細胞生物  轉運蛋白  新陳代謝  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat,  (predicted: Human, Mouse, Chicken, Dog, Cow, Horse, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 12kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human EIF4B around the phosphorylation site of Thr70
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008].

Function:
Regulates eIF4E activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.

Subunit:
Hypophosphorylated EIF4EBP1 competes with EIF4G1/EIF4G3 to interact with EIF4E; insulin stimulated MAP-kinase (MAPK1 and MAPK3) or mTORC1 phosphorylation of EIF4EBP1 causes dissociation of the complex allowing EIF4G1/EIF4G3 to bind and consequent initiation of translation. Interacts with RPTOR.

Post-translational modifications:
Phosphorylated on serine and threonine residues in response to insulin, EGF and PDGF. Phosphorylation at Thr-37, Thr-46, Ser-65 and Thr-70 is regulated by mTORC1. Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the eIF4E-binding protein family.

Database links:

Entrez Gene: 1978 Human

Entrez Gene: 13685 Mouse

Entrez Gene: 116636 Rat

Omim: 602223 Human

SwissProt: Q13541 Human

SwissProt: Q60876 Mouse

SwissProt: Q62622 Rat

Unigene: 411641 Human

Unigene: 6700 Mouse

Unigene: 11161 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 91精品久久久久久久久中文字幕 | 99久久影视 | 国产精成人品 | 蜜臀av免费一区二区三区久久乐 | 亚洲最新在线视频 | 狠狠艹夜夜艹 | 综合色在线观看 | 国产成人精品午夜福利 | 成人激烈床戏免费观看网站 | 欧美日产国产新一区 | wwwwww日本| 特级毛片爽WWW免费版 | 成年人视频在线观看免费 | 在线免费一级片 | 人妻一本久道久久综合久久鬼色 | 日韩欧美精品一区二区三区经典 | 国产免费永久在线观看 | 无码天堂亚洲国产AV麻豆 | 久久久久国产精品一区二区三区 | 911色_911色sss主站色播 | 亚洲精品久久久久中文字幕 | 高H紫黑色的又粗又上翘 | 国产亚洲精品一区二555 | 国产日产久久久久久 | 日韩啪啪免费视频 | 久久亚洲美女精品国产精品 | 中国XXXXXL19免费视频 | 亚洲精品aⅴ中文字幕乱码 欧美日韩一区免费 | 日本伦理在线视频 | 亚洲影院丰满少妇中文字幕无码 | 离异熟女不戴套456 免费操人 | ww939766com永久免费 | 亚洲成人aa | 五月激情综合 | 9191久久久久久久久久久 | 亚洲成人伊人 | 欧美性猛交视频 | 国产激情з∠视频一区二区 | 中文字字幕在线中文乱码范文 | 在线观看青青草 | 91精品久久久久久久久久不卡 |