97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
江苏少妇性BBB搡BBB爽爽爽,成人看片人aa,人妻无码AV中文系列久久兔费
Rabbit Anti-phospho-eIF4EBP1(Thr70)/BF647 Conjugated antibody (bs-14550R-BF647)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-14550R-BF647
英文名稱 Rabbit Anti-phospho-eIF4EBP1(Thr70)/BF647 Conjugated antibody
中文名稱 BF647標(biāo)記的磷酸化eIF4E結(jié)合蛋白抗體
別    名 eIF4EBP1 (phospho T70); eIF4EBP1 (phospho Thr70); p-eIF4EBP1 (Thr70); eIF4EBP1; Eukaryotic translation initiation factor 4E binding protein 1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E BP1; 4EBP1; BP 1; BP1; eIF4E binding protein 1; eIF4E-binding protein 1; Eukaryotic translation initiation factor 4E binding protein 1; MGC4316; PHAS I; PHASI; PHAS-I; PHAS; 4E-BP1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; Phosphorylated heat and acid stable protein regulated by insulin 1; 4EBP1_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 細(xì)胞生物  轉(zhuǎn)運蛋白  新陳代謝  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat,  (predicted: Human, Mouse, Chicken, Dog, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 12kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human EIF4B around the phosphorylation site of Thr70
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008].

Function:
Regulates eIF4E activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.

Subunit:
Hypophosphorylated EIF4EBP1 competes with EIF4G1/EIF4G3 to interact with EIF4E; insulin stimulated MAP-kinase (MAPK1 and MAPK3) or mTORC1 phosphorylation of EIF4EBP1 causes dissociation of the complex allowing EIF4G1/EIF4G3 to bind and consequent initiation of translation. Interacts with RPTOR.

Post-translational modifications:
Phosphorylated on serine and threonine residues in response to insulin, EGF and PDGF. Phosphorylation at Thr-37, Thr-46, Ser-65 and Thr-70 is regulated by mTORC1. Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the eIF4E-binding protein family.

Database links:

Entrez Gene: 1978 Human

Entrez Gene: 13685 Mouse

Entrez Gene: 116636 Rat

Omim: 602223 Human

SwissProt: Q13541 Human

SwissProt: Q60876 Mouse

SwissProt: Q62622 Rat

Unigene: 411641 Human

Unigene: 6700 Mouse

Unigene: 11161 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 91精品片 | 九九夜夜| 国产午夜av秒播在线观看 | 粗大猛烈进出呻吟声视频 | 我的初次内射欧美成人影视 | 欲望之岛在线免费观看 | 久久久国产精品萌白酱免费 | 久久久久综合一区二区三区 | 免费观看一级特黄欧美大片 | 一级片视频免费观看 | 国产成人a在线视频免费 | 一区二区三区精品视频免费看 | 理论片麻豆 | 精品久久久久久久久久中文字幕 | 午夜影院在线午夜影院在线观看 | 午夜a毛片 | 91视频分类| 无遮无挡爽爽免费视频 | 男人操女人高清视频 | 久久精品人妻系列无码专区 | 欧美精品久久久久 | 色七七av | 久久精品水蜜桃AV综合天堂 | 一本大道久久a久久精二百 国产av一级片日韩二区 | 18禁勿入午夜网站入口 | 成在线人AV无码高潮喷水 | 国产精品69久久久久孕妇欧美 | 欧美黄色成人 | 国产专区2 | 97免费超碰 | 亚洲爆乳成AV人在线视水卜 | 国产三级精品三级在 | 國產精品倫一區二區三級視頻 | 亚洲精品视频在线观看视频 | 人妻系列无码专区久久五月天 | av免费播放网址 | 国产大BBWBBWHD视频 | 日本少妇人妻XXXXⅩ18 | 亚洲欧洲国产精品久久 | 精品国产综合乱码久久久久久 | av免费网站在线 |