97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
色婷婷久久久久swag精品,1024在线观看你懂的,裸体男同自慰gay网站
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-S1P/Subtilisin isozyme 1/APC Conjugated antibody (bs-19355R-APC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-19355R-APC
英文名稱 Rabbit Anti-S1P/Subtilisin isozyme 1/APC Conjugated antibody
中文名稱 APC標記的枯草桿菌蛋白酶同工酶1抗體
別    名 kexin isozyme 1; KIAA0091; MBTP1_HUMAN; MBTPS1; membrane bound transcription factor peptidase, site 1; MGC138711; MGC138712; PCSK8; S1P; S1P endopeptidase; Site 1 protease; SKI 1; SKI1; Subtilisin isozyme 1; Subtilisin/kexin isozyme 1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  表觀遺傳學  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Chicken, Rabbit, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 96kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human S1P/Subtilisin isozyme 1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction. [provided by RefSeq, Feb 2014]

Function:
Serine protease that catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF, GNPTAB and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysosomes.

Subunit:
Processes precursors containing basic and hydrophobic/aliphatic residues at P4 and P2, respectively, with a relatively relaxed acceptance of amino acids at P1 and P3.

Subcellular Location:
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein.

Tissue Specificity:
Widely expressed.

Post-translational modifications:
The 148 kDa zymogen is processed progressively into two membrane-bound 120 and 106 kDa forms in the endoplasmic reticulum, and late into a secreted 98 kDa form. The propeptide is autocatalytically removed through an intramolecular cleavage after Leu-186. Further cleavage generates 14, 10, and 8 kDa intermediates.

Similarity:
Belongs to the peptidase S8 family.
Contains 1 peptidase S8 domain.

Database links:

Entrez Gene: 8720 Human

SwissProt: Q14703 Human

SwissProt: Q9WTZ2 Mouse

SwissProt: Q9WTZ3 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 欧美成人精品高清在线观看 | 2019理论片一级 | 欧美va免费高清在线观看 | 孩交精品XXXX视频视频 | 国产精品欧美一区二区 | 国产区一区二区 | 欧美黑人狂躁日本寡妇 | 91精品中文在线 | 无码人妻aⅴ一区二区三区 色啪视频 | 亚洲性专区 | 97视频在线 | 国产亚洲h网综合h网 | 性欧美18一19sex性欧美 | 四虎亚洲精品私库AV在线 | 免费午夜网站 | 天天插天天色 | 香港三级日本三级韩国三级 | 国产日韩亚洲欧美主播精品 | 精品欧美无人区乱码毛片 | 中文字幕免费亚洲 | 国产精品在线看 | 麻豆疯狂做受xxxx高潮视频 | 中文字幕一区日韩精品欧美 | 免费视频18上在线观看 | 好吊操视频 | 中字幕视频在线永久在线 | 刮伦人妇a片1级 | 亚洲国产精品成人午夜在线观看 | 亚洲精品99999 | 在线观看成年人网站 | 婷婷丁香亚洲色综合91 | 欧美黄色一级网站 | 被夫の上司に犯中文字幕 | av网站免费在线播放 | avtt香蕉久久 | 久久青青草原国产精品最新片 | 久精品久久 | 床震吃胸膜奶免费视频 | 草草亚洲视频 | 亚洲AⅤ无码精品色情午在线 | 成人一区二区三区在线观看 |