97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
色婷婷久久久久swag精品,1024在线观看你懂的,裸体男同自慰gay网站
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-S1P/Subtilisin isozyme 1/APC Conjugated antibody (bs-19355R-APC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-19355R-APC
英文名稱 Rabbit Anti-S1P/Subtilisin isozyme 1/APC Conjugated antibody
中文名稱 APC標記的枯草桿菌蛋白酶同工酶1抗體
別    名 kexin isozyme 1; KIAA0091; MBTP1_HUMAN; MBTPS1; membrane bound transcription factor peptidase, site 1; MGC138711; MGC138712; PCSK8; S1P; S1P endopeptidase; Site 1 protease; SKI 1; SKI1; Subtilisin isozyme 1; Subtilisin/kexin isozyme 1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  表觀遺傳學  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Chicken, Rabbit, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 96kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human S1P/Subtilisin isozyme 1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction. [provided by RefSeq, Feb 2014]

Function:
Serine protease that catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF, GNPTAB and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysosomes.

Subunit:
Processes precursors containing basic and hydrophobic/aliphatic residues at P4 and P2, respectively, with a relatively relaxed acceptance of amino acids at P1 and P3.

Subcellular Location:
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein.

Tissue Specificity:
Widely expressed.

Post-translational modifications:
The 148 kDa zymogen is processed progressively into two membrane-bound 120 and 106 kDa forms in the endoplasmic reticulum, and late into a secreted 98 kDa form. The propeptide is autocatalytically removed through an intramolecular cleavage after Leu-186. Further cleavage generates 14, 10, and 8 kDa intermediates.

Similarity:
Belongs to the peptidase S8 family.
Contains 1 peptidase S8 domain.

Database links:

Entrez Gene: 8720 Human

SwissProt: Q14703 Human

SwissProt: Q9WTZ2 Mouse

SwissProt: Q9WTZ3 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 国语对白嫖老妇胖老太 | 99热9| 久久精品在线 | 国产在线精品一区二区在线看 | 蜜桃av一区二区三区 | 日韩精品免费一区二区三区竹菊 | 欧美巨大另类极品videosbest | 国语对白乱子 | 四虎蜜桃 | 国产成人精品久久二区二区 | 成人亚洲黄色 | 97人人模人人爽人人少妇 | 永久免费啪啪的网站入口 | 美女高潮无遮挡喷水视频 | 午夜成年| 黄色一级日本 | 亚洲综合色婷婷六月丁香宅男大增 | 成本人在线观看视频网站 | 人人草人人做人人爱 | 精品久久伊人99热超碰 | 色悠综合| 亚洲人成网站在线观看妞妞网 | 99re8在线精品视频免费播放 | 国产视频久久网 | 男人插女人逼逼视频 | 欧美激情第五页 | 欧美xxxx色视频在线观看 | 国产成年无码久久久免费 | 美女被久久久 | 麻豆精品国产入口 | 欧美中文字幕第一页 | 亚洲成AV人片一区二区密柚 | 天天躁日日躁狠狠躁aab吃奶 | 日韩欧精品无码三级片 | 丁香五月综合缴清中文 | 亚洲精品美女视频在线观看 | 久久久亚洲精品中文字幕 | 国产精品午夜一区二区欲梦 | 久久97精品 | 欧美xxxx做受欧美88 | 99精品观看 |