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Rabbit Anti-NLRP14/AP Conjugated antibody (bs-19286R-AP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-19286R-AP
英文名稱 Rabbit Anti-NLRP14/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的NLRP14蛋白抗體
別    名 CLR11.2; GC-LRR; LRR and PYD domains-containing protein 14; NACHT; NACHT, leucine rich repeat and PYD containing 14; NACHT, LRR and PYD containing protein 14; NACHT, LRR and PYD domains-containing protein 14; NAL14_HUMAN; Nalp-iota; NALP14; NLR family, pyrin domain containing 14; NLRP14; NOD5; Nucleotide-binding oligomerization domain protein 5; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 14; PAN8.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  細胞凋亡  結合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, 
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 125kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NLRP14
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq, Jul 2008]

Function:
May be involved in inflammation and spermatogenesis.

Tissue Specificity:
Testis-specific.

DISEASE:
In the testis, expressed mainly in A dark spermatogonia, mid and late spermatocytes and spermatids but not in mitotically active A pale and B spermatogonia.

Similarity:
Belongs to the NLRP family.
Contains 1 DAPIN domain.
Contains 11 LRR (leucine-rich) repeats.
Contains 1 NACHT domain.

Database links:

Entrez Gene: 338323 Human

Omim: 609665 Human

SwissProt: Q86W24 Human

SwissProt: Q6B966 Mouse

Unigene: 449637 Human

Unigene: 618600 Human

Unigene: 35644 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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