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Rabbit Anti-FbxL7/Gold Conjugated antibody (bs-16043R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-16043R-Gold
英文名稱 Rabbit Anti-FbxL7/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的FbxL7蛋白抗體
別    名 AL023057; D230018M15Rik; F Box and Leucine Rich Repeat Protein 7; F box protein FBL6/FBL7; F box/LRR-repeat protein 7; F-box and leucine-rich repeat protein 7; F-box protein FBL6/FBL7; F-box/LRR-repeat protein 7; FBL 6; FBL 7; FBL6; FBL7; FBXL 7; FBXL7; FBXL7_HUMAN; FLJ11609; KIAA0840; MGC102204.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  干細(xì)胞  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 55kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FbxL7
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
This gene encodes a member of the F-box protein family which is characterized by a 42-48 amino acid motif, the F-box, which binds to the S-phase kinase-associated protein 1 (Skp1) protein. The F-box proteins constitute one of the four subunits of E3 ubiquitin protein ligases called SCFs (SKP1-Cul1-F-box), which play a role in phosphorylation-dependent ubiquitination of proteins. The F-box proteins are divided into 3 subfamilies based on the other domain in the protein: F-box proteins that also have a WD-40 domain (Fbws subfamily), F-box proteins that also have leucine-rich repeats (Fbls subfamily) and F-box proteins that contain other motifs or lack known protein-interaction domains (Fbxs subfamily). The protein encoded by this gene belongs to the Fbls subfamily. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]

Function:
Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.

Similarity:
Contains 1 F-box domain. Contains 11 LRR (leucine-rich) repeats.

Database links:

Entrez Gene: 23194 Human

Entrez Gene: 448987 Mouse

Omim: 605656 Human

SwissProt: Q9UJT9 Human

SwissProt: Q5BJ29 Mouse

Unigene: 433057 Human

Unigene: 76798 Human

Unigene: 253378 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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