97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国产天堂av在线,高清视频在线播放,国产精品99久久
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-Guanylate Cyclase/APC Conjugated antibody (bs-16371R-APC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-16371R-APC
英文名稱 Rabbit Anti-Guanylate Cyclase/APC Conjugated antibody
中文名稱 APC標記的鳥苷酸環(huán)化酶/GCS-β-2/GCS-β2抗體
別    名 GC SB2; GCS BETA 2; GTP pyrophosphate lyase; Guanylate cyclase 1 soluble beta 2; GCYA2_HUMAN; Guanylate cyclase soluble beta 2; Guanylate cyclase soluble beta 2 chain; Guanylate cyclase soluble subunit beta 2; Gucy1b2; Gucy1b2a; Gucy1b2b; SGC; Soluble guanylate cyclase beta 2.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細胞生物  信號轉(zhuǎn)導(dǎo)  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Horse, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 82kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Guanylate Cyclase
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
產(chǎn)品介紹 background:
Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble form, known as GCS or sGC, act as receptors for nitric oxide. The membrane-bound receptor form, known as GC, are peptide hormone receptors. GCS is a cGMP-synthesizing enzyme, which is the major receptor for the neurotransmitter nitric oxide (NO). It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme containing heterodimer, consisting of one ?subunit and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide, which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity. The distribution of the beta-2 subunit seems to be much more restricted than the beta-1 subunit, with predominant expression in kidney and liver

Function:
Guanylate Cyclase is an heterodimer of an alpha and a beta chain. Its enzymatic activity transforms GTP to GMP releasing a diphosphate. It binds 1 or 2 hemes per heterodimer. It is activated by nitric oxide in the presence of magnesium or manganese ions. There are two types of guanylate cyclase: soluble form and membrane-associated receptor form.

Subunit:
Heterodimer of an alpha and a beta chain.

Subcellular Location:
Cytoplasmic.

Tissue Specificity:
Isoform 1 is expressed in fetal brain, liver, colon, endothelium and testis. Isoform 2 is expressed only in liver, colon and endothelium.

Similarity:
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Contains 1 guanylate cyclase domain.

Database links:

Entrez Gene: 2974 Human

Entrez Gene: 239134 Mouse

Entrez Gene: 25206 Rat

Omim: 603695 Human

SwissProt: O75343 Human

SwissProt: Q6XE41 Mouse

SwissProt: P22717 Rat

Unigene: 411573 Human

Unigene: 10933 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 国产精品久久久不卡 | 学生在线精品一区二区 | 爽好久久久欧美精品 | 一级片免费在线看 | 中国丰满大乳乳液 | 亚洲韩国欧洲国产日产av | 国99精品无码一区二区三区 | 久久国产品 | 午夜精品射精入后重之免费观看 | 人妻系列无码专区无码专区 | 精品人伦一区二区三区蜜桃视频 | 国产伦精品一区二区三区网站 | 亚洲成人av免费观看 | 免费观看黄色av | 窝窝人体色www | 91老司机福利 | 亚洲一区二区三区网站 | 日本拍拍免费观看片成人 | 免费超级淫片日本高清视频 | 欧美大黑BBB | 免费不卡av网站 | 久久精品中文字幕一区二区三区 | 久久久久高清毛片一级 | 亚洲丁香婷婷久久一区二区 | 黄视频福利 | 国产一级黄色片免费 | 可以免费看av | 中文字幕之中文字幕 | 永久免费不卡的AV网站 | 色婷婷五月综合亚洲影院 | 全免费午夜一级毛片真人 | 免费无码又爽又刺激高潮视频 | 亚洲精品永久在线观看 | 中文无字幕一区二区三区 | 国产在线视频在线观看 | 日本人一级片 | 亚洲呦女专区 | 青青草狠狠干 | 18禁勿入午夜网站入口 | 欧美性受xxxx黑人x丫x性爽 | 亚洲日韩欧美一区久久久久我 |