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Rabbit Anti-TRIM29 (acetyl K116)/AP Conjugated antibody (bs-16731R-AP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-16731R-AP
英文名稱 Rabbit Anti-TRIM29 (acetyl K116)/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的乙酰化TRIM29蛋白抗體
別    名 Ataxia telangiectasia group D associated protein; Ataxia telangiectasia group D-associated protein; ATDC; FLJ36085; TRI29_HUMAN; TRIM 29; TRIM29; Tripartite motif containing 29; Tripartite motif containing protein 29; Tripartite motif protein 29; Tripartite motif protein TRIM29; Tripartite motif-containing protein 29.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產品類型 乙酰化抗體 
研究領域 細胞生物  免疫學  信號轉導  轉錄調節因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Pig, Cow, Rabbit, )
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 66kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised acetylpeptide derived from human TRIM29 around the acetylation site of K116
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype. [provided by RefSeq, Jul 2008]

Function:
It is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line.

Subcellular Location:
Cytoplasm. Colocalizes with intermediate filaments.

Tissue Specificity:
Expressed in placenta, prostate and thymus.

Post-translational modifications:
Constitutively phosphorylated by PKC on serine/threonine in A431 cells.

Similarity:
Contains 1 B box-type zinc finger.

Database links:

Entrez Gene: 23650 Human

Entrez Gene: 525062 Cow

Entrez Gene: 72169 Mouse

Entrez Gene: 300656 Rat

Omim: 610658 Human

SwissProt: Q14134 Human

SwissProt: Q8R2Q0 Mouse

Unigene: 504115 Human

Unigene: 273277 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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