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Rabbit Anti-IPPK/BF350 Conjugated antibody (bs-16687R-BF350)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-16687R-BF350
英文名稱 Rabbit Anti-IPPK/BF350 Conjugated antibody
中文名稱 BF350標記的IPPK蛋白抗體
別    名 6)P5 2-kinase; 6-pentakisphosphate 2-kinase; bA476B13.1 (novel protein); C9orf12; inositol 1,3,4,5,6 pentakisphosphate 2 kinase; Inositol pentakisphosphate 2 kinase; Inositol-1; Inositol-pentakisphosphate 2-kinase; Ins; Ins(1; InsP5 2 kinase; InsP5 2-kinase; INSP5K2; IPK1 homolog; IPPK; IPPK_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Cow, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 56kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IPPK
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The protein encoded by this gene is a kinase that phosphorylates position 2 of inositol-1,3,4,5,6-pentakisphosphate to form inositol-1,2,3,4,5,6-hexakisphosphate (InsP6). InsP6 has a variety of functions, including stimulation of DNA repair, endocytosis, and mRNA export. [provided by RefSeq, Nov 2010]

Function:
Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). InsP6 is involved in many processes such as mRNA export, non-homologous end-joining, endocytosis, ion channel regulation. It also protects cells from TNF-alpha-induced apoptosis.

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Ubiquitously expressed, with high expression in heart, brain, testis and placenta.

Similarity:
Belongs to the IPK1 type 2 family.

Database links:

Entrez Gene: 64768 Human

Entrez Gene: 75678 Mouse

Entrez Gene: 306808 Rat

SwissProt: Q9H8X2 Human

SwissProt: Q6P1C1 Mouse

SwissProt: Q5PXE9 Rat

Unigene: 459896 Human

Unigene: 713775 Human

Unigene: 390586 Mouse

Unigene: 211702 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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