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Rabbit Anti-LARP1/BF647 Conjugated antibody (bs-17101R-BF647)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-17101R-BF647
英文名稱 Rabbit Anti-LARP1/BF647 Conjugated antibody
中文名稱 BF647標記的LARP1蛋白抗體
別    名 1810024J12Rik; 3110040D16Rik; KIAA0731; La related protein; La ribonucleoprotein domain family, member 1; LARP; MGC19556; mKIAA0731; rCG_32791; RGD1306683; RP23-293I3.7.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  細胞凋亡  結合蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, )
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 124kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LARP1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
LARP1 is a 1,096 amino acid protein belonging to the LARP family. LARP1 contains two conserved regions, one that shares homology with La/SSB proteins and one that is conserved only across LARP family proteins. Within the La/SSB conserved region, LARP1 contains a HTH La-type RNA-binding domain, which may indicate a role in RNA stabalization and folding. Upon DNA damage, LARP1 is phosphorylated by ATR or ATM. LARP1 interacts with many signaling intermediate proteins, including 14-3-3. Widely expressed, LARP1 levels are highest in heart. LARP1 exists as three isoforms produced by alternative splicing.

Function:
LARP1 belongs to the LARP family and contains 1 HTH La-type RNA-binding domain.

Subunit:
Interacts with PABPC1/PABP. Associates with the mTORC1 complex. Interacts with EIF4E.

Subcellular Location:
Cytoplasm

Similarity:
Belongs to the LARP family.
Contains 1 HTH La-type RNA-binding domain.

Database links:

Entrez Gene: 23367 Human

Omim: 612059 Human

SwissProt: Q6PKG0 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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