97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
长江有色金属网行情报价,毛片免费高清,伊人中文字幕在线
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-HPS2/BF594 Conjugated antibody (bs-17380R-BF594)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-17380R-BF594
英文名稱 Rabbit Anti-HPS2/BF594 Conjugated antibody
中文名稱 BF594標記的HPS2蛋白抗體
別    名 Adapter related protein complex 3 beta 1 subunit; Adapter-related protein complex 3 subunit beta-1; Adaptor protein complex AP-3 subunit beta-1; Adaptor protein complex AP3 beta1 subunit; ADTB3; ADTB3A; AP-3 complex subunit beta-1; AP3 complex beta1 subunit; AP3B1; AP3B1_HUMAN; Beta-3A-adaptin; Beta3A adaptin; Clathrin assembly protein complex 3 beta 1 large chain; Clathrin assembly protein complex 3 beta-1 large chain; HPS; PE.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  信號轉導  轉運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Cat,  Xenopus laevis)
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 121kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HPS2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2012]

Function:
Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles.

Subcellular Location:
Golgi apparatus. Cytoplasmic vesicle > clathrin-coated vesicle membrane. Golgi apparatus. Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.

Tissue Specificity:
Ubiquitously expressed.

Post-translational modifications:
Phosphorylated on serine residues.

DISEASE:
Defects in AP3B1 are the cause of Hermansky-Pudlak syndrome type 2 (HPS2) [MIM:608233]. Hermansky-Pudlak syndrome (HPS) is a genetically heterogeneous, rare, autosomal recessive disorder characterized by oculocutaneous albinism, bleeding due to platelet storage pool deficiency, and lysosomal storage defects. This syndrome results from defects of diverse cytoplasmic organelles including melanosomes, platelet dense granules and lysosomes. Ceroid storage in the lungs is associated with pulmonary fibrosis, a common cause of premature death in individuals with HPS. HPS2 differs from the other forms of HPS in that it includes immunodeficiency in its phenotype and patients with HPS2 have an increased susceptibility to infections.

Similarity:
Belongs to the adaptor complexes large subunit family.

Database links:

Entrez Gene: 767602 Cow

Entrez Gene: 403459 Dog

Entrez Gene: 8546 Human

Entrez Gene: 11774 Mouse

Entrez Gene: 100049670 Pig

Entrez Gene: 443724 Xenopus laevis

Omim: 603401 Human

SwissProt: Q32PG1 Cow

SwissProt: Q7YRF1 Dog

SwissProt: O00203 Human

SwissProt: Q9Z1T1 Mouse

Unigene: 532091 Human

Unigene: 21185 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 日韩中文字幕手机在线观看 | 人妻人人澡人人添人人爽 | 国产一级强片在线观看av | 提莫影院AV毛片入口 | 16p亚洲 | 国产97视频在线 | 国产毛片精品 | 国产农村女人一级毛片了 | 国产精品久久久久久AV福利 | 亚洲爆乳成AV人在线视水卜 | 一区视频免费观看 | 99久久综合狠狠综合 | 日韩中文字幕手机在线观看 | 狠狠躁夜夜躁人人躁婷婷视频 | 亚洲色图综合 | 一区二区福利 | 日本精品一区二区三区四区 | 精品国内二区三区 | 亚洲成AV人片在线观看橙子 | 中文字幕在线观看欧美 | 一二三四日韩 | 国产精品特级片 | 男人和女人做爽爽视频免费 | 欧美日韩亚洲免费 | 在公车上拨开内裤进入毛片 | 在线观看免费一区 | 一a毛片| 一区二区三区波多野结衣在线观看 | 国产精品欧美精品日韩精品 | 一本久久A精品一区二区 | aV无码久久久久不卡蜜桃 | 久久网站av | 性xxxx乱又伦 | 亚洲综合无码日韩 | 国产黄大片在线观看画质优化 | 韩国中文字幕在线观看 | 99精品视频在线看 | 女人和拘做受全程看免费软件 | 亚洲美国产亚洲AV | 蜜桃天堂| 逼自拍偷拍自拍天堂偷拍 |