97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
麻豆男女午夜福利视频,国产人与动牲交毛长,爱爱毛片视频
Rabbit Anti-phospho-HIRA (Thr555)/Gold Conjugated antibody (bs-17406R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-17406R-Gold
英文名稱 Rabbit Anti-phospho-HIRA (Thr555)/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的磷酸化HIRA蛋白抗體
別    名 HIRA (phospho T555); p-HIRA (phospho T555); DGCR1; DGGR 1; DGGR1; DiGeorge critical region gene 1; HIR; HIR histone cell cycle regulation defective homolog A; HIRA; HIRA protein; HIRA_HUMAN; Protein HIRA; TUP 1; TUP1; TUP1 like enhancer of split protein 1; TUP1-like enhancer of split protein 1; TUPLE 1; TUPLE1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  干細(xì)胞  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 112kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human HIRA around the phosphorylation site of Thr555
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq, Jul 2008]

Function:
Cooperates with ASF1A to promote replication-independent chromatin assembly. Required for the periodic repression of histone gene transcription during the cell cycle. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.

Subcellular Location:
Nucleus. Nucleus > PML body. Primarily, though not exclusively, localized to the nucleus. Localizes to PML bodies immediately prior to onset of senescence.

Tissue Specificity:
Expressed at high levels in kidney, pancreas and skeletal muscle and at lower levels in brain, heart, liver, lung, and placenta.

Post-translational modifications:
Sumoylated. Phosphorylated by CDK2/CCNA1 and CDK2/CCNE1 on Thr-555 in vitro. Also phosphorylated on Thr-555 and Ser-687 in vivo.

Similarity:
Belongs to the WD repeat HIR1 family.
Contains 8 WD repeats.

Database links:

Entrez Gene: 7290 Human

Entrez Gene: 15260 Mouse

Omim: 600237 Human

SwissProt: P54198 Human

SwissProt: Q61666 Mouse

Unigene: 474206 Human

Unigene: 15694 Mouse

Unigene: 453041 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 亚洲福利国产精品17p | 国产一区二区四区在线观看 | 边勾边做1V1H顾慕琛 | 国产精品香蕉在线观看网 | 亚洲一区二区视频在线观看 | 国内一区二区视频 | 国产又黄又硬又粗 | 日本福利在线 | 国产欧美一区二区三区视频 | 97无码视频在线看视频 | 亚洲国产精品高清在线第1页 | 操碰久久 | 人人射人人草 | 国产性生大片免费观看性 | 亚洲日韩av片在线观看 | 国产农村女人一级毛片了 | 内射少妇一区27P | 一a毛片 | 人妻丰满熟妇AV无码区乱 | 亚洲中文字幕无码久久 | 国产成人亚洲影院在线播放 | av免播放| 国产精品乱码精品久久久 | 久久精品18国产99re5 | 成人毛片18女人毛片 | 91精品国产综合久久久久久蜜月 | 老司机伊人网 | 超碰69| 一区二区三区四区日韩 | 性生大片免费观看网站蜜芽 | 亚洲午夜福利在线观看老司机 | 国产91在线观看 | 国产精品色婷婷99久久精品 | 免费人成再在线观看网站 | 亚洲中文久久精品无码软件 | 亚洲美国产亚洲AV | 91精品国产综合久久久久久蜜月 | 97九色 | 国产高清一级毛片在线不卡 | 亚洲欧美日韩天堂一区二区 | 91国产一区 |