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Rabbit Anti-Skuld/AP Conjugated antibody (bs-17512R-AP)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-17512R-AP
英文名稱 Rabbit Anti-Skuld/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的Skuld蛋白抗體
別    名 CG9936-PC isoform C; Cg9936-pd isoform d; Jlkjlkj; MED13_DROME; Med13; Mediator complex subunit 13; Pap/DTRAP240; Protein blind spot; skd; Transcriptional coactivator blind spot; Trap240.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 發育生物學  轉錄調節因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 280kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Fruit fly Skuld
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Sklud is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Required for leg and eye development and macrochaete specification or differentiation. Negatively regulates sex comb development.

Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). Required for leg and eye development and macrochaete specification or differentiation. Negatively regulates sex comb development. Required for activated transcription of the MtnB and MtnD genes.

Subunit:
Component of the Cdk8 module of the Mediator complex, composed of CycC, Cdk8, kto and skd.

Subcellular Location:
Nuclear

Similarity:
Belongs to the Mediator complex subunit 13 family.

Database links:

Entrez Gene: 43906 Fruit fly (Drosophila melanogaster)

SwissProt: Q7KTX8 Fruit fly (Drosophila melanogaster)



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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