97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
50岁四川熟女A片,毛片免费在线视频,高清精品
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-NCK adaptor protein 1/2/BF488 Conjugated antibody (bs-7377R-BF488)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-7377R-BF488
英文名稱 Rabbit Anti-NCK adaptor protein 1/2/BF488 Conjugated antibody
中文名稱 BF488標記的NCK銜接蛋白1/2抗體
別    名 Nck 1/2; NCK adaptor protein 1 + 2 GRB4; melanoma NCK protein; MGC12668; NCK; NCK adaptor protein 1; NCK adaptor protein 2; NCK tyrosine kinase; NCKalpha; NCKbeta; NCK1_HUMAN;NCK12_HUMAN; non catalytic region of tyrosine kinase; noncatalytic region of tyrosine kinase, beta; SH2/SH3 adaptor protein NCK alpha; SH2/SH3 adaptor protein NCK beta  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  信號轉導  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 43kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NCK adaptor protein 1/2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Jun 2010]

Function:
NCK1 is one of the adaptor proteins which mediate specific protein-protein interactions in signaling processes. Adaptor proteins usually contain several domains like SH2 and SH3 which allow specific interactions with other specific proteins. NCK1 and NCK2 show high sequence identity (68%) and have three SH3 domains and a C-terminal SH2 domain. Both of them bind receptor tyrosine kinases such as PDGFR and other tyrosine phosphorylated proteins via their SH2 domains. Various molecules which interact with SH domains of Nck and regulate signaling process of actin cytoskeleton reorganization have been identified. Ncks are thought to have important functions in the development of mesodermal structures during embryogenesis, linked to a role in cell movement and cytoskeletal reorganization. Ncks also have a function in modulating mRNA translation at the level of initiation by interacting eukayotic initiation factor 2 (eIF2). Under stressed conditions, protein synthesis is reduced by inhibiting the activity of eIF2 through phosphorylation, transiently inhibiting recycling of eIF2 into its active form.

Subcellular Location:
Cytoplasm. Endoplasmic reticulum. Nucleus. Note=Mostly cytoplasmic, but shuttles between the cytoplasm and the nucleus. Import into the nucleus requires the interaction with SOCS7. Predominantly nuclear following genotoxic stresses, such as UV irradiation, hydroxyurea or mitomycin C treatments.

Post-translational modifications:
Phosphorylated on Ser and Tyr residues. Phosphorylated in response to activation of EGFR and FcERI. Phosphorylated by activated PDGFRB.

Similarity:
Contains 1 SH2 domain.
Contains 3 SH3 domains.

Database links:

Entrez Gene: 4690 Human

Entrez Gene: 8440 Human

Entrez Gene: 17973 Mouse

Entrez Gene: 17974 Mouse

Entrez Gene: 300955 Rat

Entrez Gene: 316369 Rat

Omim: 600508 Human

Omim: 604930 Human

SwissProt: O43639 Human

SwissProt: P16333 Human

SwissProt: Q8BQ28 Mouse

SwissProt: Q99M51 Mouse

SwissProt: B2RZ33 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 国产乱色精品成人免费视频 | 国产精品无码一区二区三区不卡 | 少妇粉嫩小泬喷水视频WWW | 成年肉动漫在线观看无码 | 国产成人精品午夜福利软件 | 亚洲欧美第一成人网站7777 | 伊人精品视频在线观看 | 啊v视频在线 | 亚洲人av在线 | 2020久久超碰国产精品最新 | 欧美日韩国产人妻无码 | 国产免费一区二区在线a片视频 | 恋爱的味道1在线 | 97精品人人A片免费看 | 啊灬啊灬啊灬快灬高潮了听书 | 亚洲人成网在线播放 | 国产精品久久久久久婷婷动漫 | 一本到不卡免费一区二区 | 久久国产精品精品国产 | 亚洲日产色情偷拍 | 九草视频在线观看 | 亚洲日韩av片在线观看 | 乱人伦人妻中文字幕 | 日韩啪啪免费视频 | 亚州欧美日韩 | 久久久精品国产 | 成人黄网视频在线观看 | 区区久久久狼 | 一级做a爰片久久毛片一 | 变态视频在线观看 | 欧美一级大黄大黄大色毛片小说 | 欧亚在线视频 | 欧美日韩精品一区 | 男女一区二区三区 | 99视频在线无码 | 97自拍网 | 高潮一区二区 | 久久91久久久久麻豆精品 | 夜夜爽夜夜叫夜夜高潮 | 特大黄色片 | 色老头av亚洲一区二区男男 |