97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
国产XXXX视频在线观看,亚洲一区正在播放,www.久久天堂
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-SRGAP1/HRP Conjugated antibody (bs-10671R-HRP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-10671R-HRP
英文名稱 Rabbit Anti-SRGAP1/HRP Conjugated antibody
中文名稱 辣根過氧化物酶標記的Rho GTP酶激活蛋白13抗體
別    名 ARHGAP13; FLJ22166; KIAA1304; RGD1566260; Rho GTPase activating protein 13; SLIT ROBO Rho GTPase activating protein 1; SRGAP 1; SRGP1_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  信號轉導  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit, Sheep, )
產品應用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 124kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SRGAP1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
SRGAPs contain a highly conserved overall primary structure and play an important role in the cell facilitating Slit-robo signaling in cell migration and axon guidance. SRGAP1 (Slit-robo Rho GTPase activating protein 1), also known as ARHGAP13 (Rho GTPase activating protein 13), functions as a GTPase-activating protein for Cdc42 and Rho A. Expressed in kidney, testis, lung and brain, SRGAP1 contains an FCH (Fes/CIP4 homology) domain, a Rho-GAP domain and an SH3 domain. In the presence of Slit, SRGAP1 (via its SH3 domain) binds to the CC3 motif in robo (a protein responsible for mediating the repulsive effect of Slit) with higher affinity and inhibits Cdc42 activity in a robo/SRGAP-dependent manner. More specifically, SRGAP1 increases the intrinsic GTPase activity of Cdc42, thereby converting it to its inactive, GDP-bound form. Inactivation of Cdc42 ultimately leads to a decrease in actin polymerization.

Function:
GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42.

Subunit:
Homodimer (Probable). Forms heterooligomer with SRGAP2 and SRGAP3 through its F-BAR domain. Interacts with ROBO1, CDC42 and RHOA. Interacts with FASLG.

Tissue Specificity:
Expressed in brain, lung, kidney, and testis.

Similarity:
Contains 1 FCH domain.
Contains 1 Rho-GAP domain.
Contains 1 SH3 domain.

Database links:

Entrez Gene: 57522 Human

Entrez Gene: 117600 Mouse

Entrez Gene: 314903 Rat

Omim: 606523 Human

SwissProt: Q7Z6B7 Human

SwissProt: Q91Z69 Mouse

Unigene: 210751 Human

Unigene: 593803 Human

Unigene: 288698 Mouse

Unigene: 208903 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 被两个两个黑人吃奶4P | 国产精品99久久久久久小说 | 成人黄色片在线观看 | 国产日产久久久久久 | 男人女人做爽爽18禁免费 | 久99热 | 亚洲中文字幕国产综合 | 亚洲综合无码久久精品综合 | 久久大香国产成人AV | 把女的下面扒开添视频 | 亚洲日本黄色片 | aaaaa毛片 | 欧美一级片免费观看 | 日本黄页网站免费大全1688 | 免费观看18禁无遮挡真人网站 | 成人一级视频 | 国产女教师一爽a片 | 亚洲成人资源在线观看 | 男女后进式猛烈XX00免费视频 | 俄罗斯ZOOM与人性ZOOM | 欧美日韩国产免费一区二区三区 | 日韩精品无码一区二区中文字幕 | 亚洲精品视频成人 | 水蜜桃AV无码 | 91精品一区二区三区在线观看 | 少妇毛又多又黑又大又粗 | 中文字幕av色 | 日本少妇做爰全过程二区 | 99精品在线播放 | 国产aⅴ夜夜欢一区二区三区 | 亚洲色欲色欱WWW在线 | 精品一区二区三区视频日产 | 国产精品不卡一区 | www.免费av| 一级黄色裸体片 | 久久久污 | 在线视频观看免费视频18 | 中文字幕一区日韩精品欧美 | 天天色综合合 | 欧美精品videosex极品 | 久久AV老司机精品网站导航 |