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Rabbit Anti-SPHKAP/APC Conjugated antibody (bs-17662R-APC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-17662R-APC
英文名稱 Rabbit Anti-SPHKAP/APC Conjugated antibody
中文名稱 APC標記的鞘氨醇激酶1相互作用蛋白抗體
別    名 A-kinase anchor protein SPHKAP; DKFZp781H143; DKFZp781J171; KIAA1678; MGC132614; MGC132616; SKIP; Sphingosine kinase type 1-interacting protein; SPHK1 (sphingosine kinase type 1) interacting protein; SPHK1 interactor, AKAP domain containing; ; SPHK1-interacting protein; SPHK1-interactor and AKAP domain-containing protein; sphkap; SPKAP_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  神經生物學  信號轉導  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 186kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SPHKAP
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Anchoring protein that binds preferentially to the type I regulatory subunit of c-AMP-dependent protein kinase (PKA type I) and targets it to distinct subcellular compartments. May act as a converging factor linking cAMP and sphingosine signaling pathways. Plays a regulatory role in the modulation of SPHK1.

Subunit:
Anchoring protein that binds preferentially to the type I regulatory subunit of c-AMP-dependent protein kinase (PKA type I) and targets it to distinct subcellular compartments. May act as a converging factor linking cAMP and sphingosine signaling pathways. Plays a regulatory role in the modulation of SPHK1.

Subcellular Location:
Cytoplasm. Colocalizes with SPHK1 in the cytoplasm.

Tissue Specificity:
Highly expressed in heart. Both isoforms abundantly expressed in ventricle. Also expressed in spleen, ovary and brain.

Similarity:
Belongs to the AKAP110 family.

Database links:

Entrez Gene: 80309 Human

Entrez Gene: 77629 Mouse

Omim: 611646 Human

SwissProt: Q2M3C7 Human

SwissProt: Q6NSW3 Mouse

Unigene: 436306 Human

Unigene: 154303 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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