97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
九九综合网站,黄网站色网址,无码精品一区二区三区在线A片
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-phospho-LIM Kinase 2 (Thr505)/FITC Conjugated antibody (bs-18257R-FITC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-18257R-FITC
英文名稱 Rabbit Anti-phospho-LIM Kinase 2 (Thr505)/FITC Conjugated antibody
中文名稱 FITC標記的磷酸化單絲氨酸蛋白激酶2抗體
別    名 LIM Kinase 1 (phospho T505); p-LIM Kinase 1 (phospho T505); LIM domain kinase 2; LIMK 2; LIMK-2; LIMK2; LIMK2_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產品類型 磷酸化抗體 
研究領域 細胞生物  信號轉導  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 70kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human LIM Kinase 1 around the phosphorylation site of Thr505
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. The protein encoded by this gene is phosphorylated and activated by ROCK, a downstream effector of Rho, and the encoded protein, in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. It is thought that this pathway contributes to Rho-induced reorganization of the actin cytoskeleton. At least three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro.

Subcellular Location:
Cytoplasm. Nucleus. Isoform LIMK2a is distributed in the cytoplasm and the nucleus and Cytoplasm. Nucleus. Isoform LIMK2b occurs mainly in the cytoplasm and is scarcely translocated to the nucleus.

Tissue Specificity:
Highest expression in the placenta; moderate level in liver, lung, kidney, and pancreas. LIMK2a is found to be more abundant then LIMK2b in liver, colon, stomach, and spleen, while in brain, kidney, and placenta LIMK2b is the dominant form. In adult lung, both LIMK2a and LIMK2b is nearly equally observed.

Post-translational modifications:
Phosphorylated on serine and/or threonine residues by ROCK1.

Similarity:
Belongs to the protein kinase superfamily.
TKL Ser/Thr protein kinase family.
Contains 2 LIM zinc-binding domains.
Contains 1 PDZ (DHR) domain.
Contains 1 protein kinase domain.

Database links:

Entrez Gene: 3985 Human

Entrez Gene: 16886 Mouse

Entrez Gene: 29524 Rat

Omim: 601988 Human

SwissProt: P53671 Human

SwissProt: O54785 Mouse

SwissProt: P53670 Rat

Unigene: 474596 Human

Unigene: 124176 Mouse

Unigene: 390323 Mouse

Unigene: 442189 Mouse

Unigene: 11013 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 精品欧美一区二区中文字幕视频 | 国产精品久久久久久 | 国产无遮挡色视频免费观看性色 | 中文字幕av一区二区三区 | m麻豆传媒映画 | 国产精品成人免费视频 | 精品熟女碰碰人人A久久 | 日韩亚洲国产中文字幕欧美 | 国产毛片毛片毛片毛片毛片 | 国产成人精品无码一区二区 | 久久频这里精品99香蕉 | 久久久久久草 | 女人被躁到高潮嗷嗷叫69 | 免费人成视频在线观看播放网站 | 男女一区二区三区 | 91精品国产色综合久久不卡蜜臀 | 国产尤物av尤物在线观看 | 伊人色亚洲 | 久久99精品久久久久久236 | 中文字幕av一区二区三区 | 99精品热在线在线观看视频 | 中文WWW新版资源在线 | 精品视频无码一区二区三区 | 野花社区www官网在线观看 | 久久久久久国产精品免费无遮挡 | 国产成人午夜性a一级毛片 涩涩久久久 | 亚洲精品亚洲人成在线观看 | 永久免费黄色 | 久久精品人妻无码一区二区三区 | 日本正能量不良网站 | H无码精品动漫在线观看导航 | 欧美1区2区3| 久久精品中文字幕一区二区三区 | 中文字幕日韩经典 | 无码人妻精品一区二区在线视频 | 日本aa在线观看 | 国产亚洲欧洲 | 一区二区三区免费看视频 | 日韩资源在线观看 | 成人欧美大片免费观看 | 久久狠狠色噜噜狠狠狠狠97 |