97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
国产精品丝袜在线观看,免费观看成人欧美WWW色,欧美11一13sex性hd
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-phospho-LIM Kinase 2 (Thr505)/BF594 Conjugated antibody (bs-18257R-BF594)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-18257R-BF594
英文名稱 Rabbit Anti-phospho-LIM Kinase 2 (Thr505)/BF594 Conjugated antibody
中文名稱 BF594標記的磷酸化單絲氨酸蛋白激酶2抗體
別    名 LIM Kinase 1 (phospho T505); p-LIM Kinase 1 (phospho T505); LIM domain kinase 2; LIMK 2; LIMK-2; LIMK2; LIMK2_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產品類型 磷酸化抗體 
研究領域 細胞生物  信號轉導  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 70kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human LIM Kinase 1 around the phosphorylation site of Thr505
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. The protein encoded by this gene is phosphorylated and activated by ROCK, a downstream effector of Rho, and the encoded protein, in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. It is thought that this pathway contributes to Rho-induced reorganization of the actin cytoskeleton. At least three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro.

Subcellular Location:
Cytoplasm. Nucleus. Isoform LIMK2a is distributed in the cytoplasm and the nucleus and Cytoplasm. Nucleus. Isoform LIMK2b occurs mainly in the cytoplasm and is scarcely translocated to the nucleus.

Tissue Specificity:
Highest expression in the placenta; moderate level in liver, lung, kidney, and pancreas. LIMK2a is found to be more abundant then LIMK2b in liver, colon, stomach, and spleen, while in brain, kidney, and placenta LIMK2b is the dominant form. In adult lung, both LIMK2a and LIMK2b is nearly equally observed.

Post-translational modifications:
Phosphorylated on serine and/or threonine residues by ROCK1.

Similarity:
Belongs to the protein kinase superfamily.
TKL Ser/Thr protein kinase family.
Contains 2 LIM zinc-binding domains.
Contains 1 PDZ (DHR) domain.
Contains 1 protein kinase domain.

Database links:

Entrez Gene: 3985 Human

Entrez Gene: 16886 Mouse

Entrez Gene: 29524 Rat

Omim: 601988 Human

SwissProt: P53671 Human

SwissProt: O54785 Mouse

SwissProt: P53670 Rat

Unigene: 474596 Human

Unigene: 124176 Mouse

Unigene: 390323 Mouse

Unigene: 442189 Mouse

Unigene: 11013 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 中文字幕日韩在线 | 一级做a爰片久久毛片一 | 欧美性生交大片免费看a片 黄色录像a级片 | 成人羞羞视频在线观看 | 俺去啦久久草在线视频 | 国产精品二区在线 | 亚洲成成熟女人专区 | 亚洲午夜精品一区二区三区 | 91老司机福利 | 综合自拍偷拍 | 久久精品人人爽人人爽 | 免费黄在线观看 | 日韩免费黄色 | 久久久无码精品成人A片小说 | 亚洲成人黄色在线观看 | 久爱www人成视频在线观看 | 欧美成人一区二区三区片免费 | 久久精品国产99久久久 | 免费成人在线观看 | 无码AV午夜福利一区 | 天地争霸美猴王国语在线观看免费 | www.色姐姐| 国产性色强伦免费看视频 | 久久久亚洲精品中文字幕 | 色视频网站在线观看 | 丰满熟妇人妻Av无码区 | 国产精品96久久久久久又黄又硬 | 秋霞福利网 | 精品国产综合乱码久久久久久 | 久久99日韩国产精品久久99 | 国产尤物小视频在线观看 | 中文字幕+乱码+中文乱码 | 国产精品久久久久久免费一级 | 国产成人精品久久免费动漫 | 国产精品乱子 | 精品国产一区天天 | 被黑人伦流澡到高潮hn小说 | 亚洲欧美综合久久久久久 | 一本到不卡免费一区二区 | 麻豆传媒一区二区三区 | 性伦欧美刺激片在线观看 |