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Rabbit Anti-MAGT1/BF350 Conjugated antibody (bs-18633R-BF350)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-18633R-BF350
英文名稱 Rabbit Anti-MAGT1/BF350 Conjugated antibody
中文名稱 BF350標記的鎂轉運蛋白1抗體
別    名 bA217H1; DKFZp564K142; FLJ14726; IAG2; IAP; Implantation-associated protein; Magnesium transporter 1; MagT1; MGC64926; MRX95; Oligosaccharyltransferase 3 homolog B; OST3B; OTTHUMP00000023589; OTTHUMP00000062081; PRO0756; RP11-217H1.1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  結合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 35kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MAGT1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a magnesium cation transporter protein that localizes to the cell membrane. This protein also associates with N-oligosaccharyl transferase and therefore may have a role in N-glycosylation. Mutations in this gene cause mental retardation X-linked type 95 (MRX95). This gene may have multiple in-frame translation initiation sites, one of which would encode a shorter protein with an N-terminus containing a signal peptide at amino acids 1-29. [provided by RefSeq, Jan 2010]

Function:
May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg2+ transport in epithelial cells.

Subunit:
Weakly associates with the oligosaccharyl transferase (OST) complex which contains at least RPN1/ribophorin I, RPN2/ribophorin II, OST48, DAD1, and either STT3A or STT3B

Subcellular Location:
Cell membrane.

Tissue Specificity:
Ubiquitous. Expressed at very low levels in brain, lung and kidney.

DISEASE:
Immunodeficiency, X-linked, with magnesium defect, Epstein-Barr virus infection and neoplasia (XMEN) [MIM:300853]: A disease characterized by CD4 lymphopenia, severe chronic viral infections, and defective T-lymphocyte activation.
Note: The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the OST3/OST6 family.
Contains 1 thioredoxin domain.

Database links:

Entrez Gene: 84061 Human

Entrez Gene: 67075 Mouse

Entrez Gene: 116967 Rat

Omim: 300715 Human

SwissProt: Q9H0U3 Human

SwissProt: Q9CQY5 Mouse

SwissProt: O35777 Rat

Unigene: 323562 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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