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Rabbit Anti-ZNF743/Gold Conjugated antibody (bs-18700R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-18700R-Gold
英文名稱 Rabbit Anti-ZNF743/Gold Conjugated antibody
中文名稱 膠體金標記的鋅指蛋白743抗體
別    名 MBD2 Interacting Zinc Finger MIZF; DKFZp434F162; HiNF-P; HINFP; HINFP_HUMAN; Histone H4 gene specific protein HiNF P; Histone H4 transcription factor; Histone nuclear factor P; MBD2 (methyl-CpG-binding protein)-interacting zinc finger protein; MBD2 interacting zinc finger 1; MBD2 interacting zinc finger protein; MBD2-interacting zinc finger protein; Methyl CpG binding protein 2 interacting zinc finger protein; Methyl-CpG-binding protein 2-interacting zinc finger protein; MIZF; ZNF 743.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 轉錄調節因子  鋅指蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 60kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZNF743
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
This gene encodes a transcription factor that interacts with methyl-CpG-binding protein-2 (MBD2), a component of the MeCP1 histone deacetylase (HDAC) complex, and plays a role in DNA methylation and transcription repression. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Aug 2011]

Function:
Transcriptional repressor that binds to the consensus sequence 5'-CGGACGTT-3' and to the RB1 promoter. Transcriptional activator that promotes histone H4 gene transcription at the G1/S phase transition in conjunction with NPAT. Also activates transcription of the ATM and PRKDC genes. Autoregulates its expression by associating with its own promoter.

Subcellular Location:
Nucleus. Associated with discrete nuclear foci.

Tissue Specificity:
Ubiquitous. Highly expressed in brain, heart, skeletal muscle, spleen, kidney, small intestine, placenta and liver.

Post-translational modifications:
Ubiquitinated. Ubiquitination may lead to proteasome-mediated degradation.

Similarity:
Contains 9 C2H2-type zinc fingers.

Database links:

Entrez Gene: 511965 Cow

Entrez Gene: 25988 Human

Entrez Gene: 102423 Mouse

Entrez Gene: 300665 Rat

Omim: 607099 Human

SwissProt: Q2TBP2 Cow

SwissProt: Q9BQA5 Human

SwissProt: Q8K1K9 Mouse

Unigene: 504091 Human

Unigene: 24570 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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