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Rabbit Anti-MEX3C/BF488 Conjugated antibody (bs-18821R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-18821R-BF488
英文名稱 Rabbit Anti-MEX3C/BF488 Conjugated antibody
中文名稱 BF488標(biāo)記的MEX3C蛋白抗體
別    名 BM 013; BM013; FLJ38871; Mex 3 homolog C C. elegans; Mex 3, C. elegans, homolog of C; MEX 3C; MEX3C; MEX3C_HUMAN; Ring finger and KH domain containing 2; RING finger and KH domain containing protein 2; RING finger and KH domain-containing protein 2; RING finger protein 194; RKHD2; RNA-binding E3 ubiquitin-protein ligase MEX3C; RNA-binding protein MEX3C; RNF194.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  結(jié)合蛋白  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 69kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MEX3C
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of a family of proteins with two K homology (KH) RNA-binding domains and a C-terminal RING-finger domain. The protein interacts with mRNA via the KH domains, and the protein shuttles between the nucleus and cytoplasm. Polymorphisms in this gene may contribute to hypertension. [provided by RefSeq, Oct 2009]

Function:
RNA-binding protein. May be involved in post-transcriptional regulatory mechanisms.

Subunit:
Interacts with USP7, which antagonizes the ability to degrade mRNA.

Subcellular Location:
Cytoplasm. Nucleus. Predominantly expressed in the cytoplasm and shuttles between the cytoplasm and the nucleus through the CRM1 export pathway.

Tissue Specificity:
Highest levels found in fetal brain and testis. Also expressed in thymus, salivary gland and uterus. Week expression in the intestine.

DISEASE:
Note=Genetic variations in MEX3C may be associated with susceptibility to essential hypertension.

Similarity:
Contains 2 KH domains.
Contains 1 RING-type zinc finger.

Database links:

Entrez Gene: 51320 Human

Entrez Gene: 240396 Mouse

Entrez Gene: 307271 Rat

Omim: 611005 Human

SwissProt: Q5U5Q3 Human

SwissProt: Q05A36 Mouse

Unigene: 465144 Human

Unigene: 24131 Mouse

Unigene: 436942 Mouse

Unigene: 8138 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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