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Rabbit Anti-SDPR/PE-Cy3 Conjugated antibody (bs-19605R-PE-Cy3)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-19605R-PE-Cy3
英文名稱 Rabbit Anti-SDPR/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標(biāo)記的磷脂酰絲氨酸結(jié)合蛋白SDPR抗體
別    名 Cavin 2; Cavin-2; Phosphatidylserine binding protein; Phosphatidylserine-binding protein; PS p68; PS-p68; Sdpr; SDPR_HUMAN; SDR; Serum deprivation response; Serum deprivation response protein; Serum deprivation-response protein.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  激酶和磷酸酶  結(jié)合蛋白  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse, Rat,  (predicted: Human, Cow, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 47kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SDPR
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.[provided by RefSeq, Sep 2009]

Function:
May play a role in targeting PRKCA to caveolae.

Subcellular Location:
Cytoplasm > cytosol. Membrane > caveola. Colocalizes with CAV1 to caveolae.

Tissue Specificity:
Highly expressed in heart and lung, and expressed at lower levels in brain, kidney, liver, pancreas, placenta, and skeletal muscle.

Post-translational modifications:
Phosphorylated on Ser residues.

Similarity:
Belongs to the PTRF/SDPR family.

Database links:

Entrez Gene: 8436 Human

Entrez Gene: 20324 Mouse

Entrez Gene: 316384 Rat

Omim: 606728 Human

SwissProt: O95810 Human

SwissProt: Q63918 Mouse

SwissProt: Q66H98 Rat

Unigene: 26530 Human

Unigene: 480575 Mouse

Unigene: 203035 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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