97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
成人影院在线,免费a级毛片在线播放 ,啪啪国产
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-SCN4B/AP Conjugated antibody (bs-20042R-AP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-20042R-AP
英文名稱 Rabbit Anti-SCN4B/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的鈉通道亞基β4抗體
別    名 SCN4B_HUMAN. Sodium channel subunit beta-4.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 心血管  神經生物學  信號轉導  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SCN4B
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The SCN4B protein modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation By similarity. The protein has been found to be expressed at a high level in dorsal root ganglia, at a lower level in brain, spinal cord, skeletal muscle and heart. Defects in SCN4B are the cause of long QT syndrome type 10 (LQT10) [MIM:611819]. Long QT syndromes are heart disorders characterized by a prolonged QT interval on the ECG and polymorphic ventricular arrhythmias. They cause syncope and sudden death in response to excercise or emotional stress. They can present with a sentinel event of sudden cardiac death in infancy.

Function:
Modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation.

Subunit:
The voltage-sensitive sodium channel consists of an ion conducting pore forming alpha-subunit regulated by one or more beta-1, beta-2, beta-3 and/or beta-4 subunits. Beta-1 and beta-3 are non-covalently associated with alpha, while beta-2 and beta-4 are covalently linked by disulfide bonds. Associates with SCN2A.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Expressed at a high level in dorsal root ganglia, at a lower level in brain, spinal cord, skeletal muscle and heart.

Post-translational modifications:
Contains a number of interchain disulfide bonds with SCN2A.

DISEASE:
Defects in SCN4B are the cause of long QT syndrome type 10 (LQT10) [MIM:611819]. Long QT syndromes are heart disorders characterized by a prolonged QT interval on the ECG and polymorphic ventricular arrhythmias. They cause syncope and sudden death in response to excercise or emotional stress. They can present with a sentinel event of sudden cardiac death in infancy.

Similarity:
Belongs to the sodium channel auxiliary subunit SCN4B (TC 8.A.17) family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.

Database links:

Entrez Gene: 6330 Human

SwissProt: Q8IWT1 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 欧美日韩亚洲中文字幕一区二区三区 | 国产一级片网站 | 国产成人愉拍精品 | 中文字幕无码肉感爆乳在线 | 日本一区二区不卡在线 | 91一区二区三区四区 | 国产V精品V欧美V日韩V | 人人摸人人操 | 温柔少妇的高潮呻吟 | 操操操操网| 亚洲一区在线日韩在线尤物 | 免费国产片 | 99久久免费国产精精品 | 看片一区二区三区 | 青青青在线视频免费观看 | 亚洲欧美色视频 | 色视频www在线播放国产人成 | 国产高清www午色夜 国产精品yjizz视频网 | 日韩精品中文字幕在线观看 | 久久久久久无码精品无码国产人妻丝瓜 | 中国视频一区二区 | 国产又大又粗又爽的毛片 | 国产成人啪精品视频免费网站 | 天天操天天干天天爽 | 国产线观看免费观看 | av大片免费看 | 偷妻无码一区二区三区动漫 | 久久WWW成人看片免费不卡 | 久久精品99久久久久久2456 | 一区二区三区日韩精品 | 亚洲精品aⅴ中文字幕乱码 欧美日韩一区免费 | 国99精品无码一区二区三区 | 欧美aaaaxxxxx精品 | VIDEOS1080P内射少妇 | 99干b| 日韩欧美在线综合 | 中文一区二区三区四区 | 欧美另类在线播放 | 精品亚洲国产成人A片在线鸭王 | 熟女人妻aⅴ一区二区三区60路 | 美国黄色片子 |