| 產(chǎn)品編號(hào) | bs-19884R-Gold |
| 英文名稱 | Rabbit Anti-PARP10/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的多腺苷二磷酸多聚酶PARP10抗體 |
| 別 名 | ADP ribosyltransferase diphtheria toxin like 10; ARTD10; PARP 10; Poly (ADP ribose) polymerase family member 10; Poly [ADP ribose] polymerase 10. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 表觀遺傳學(xué) G蛋白信號(hào) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 110kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PARP10 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: Poly(ADP-ribose) polymerases (PARPs), such as PARP10, regulate gene transcription by altering chromatin organization by adding ADP-ribose to histones. PARPs can also function as transcriptional cofactors (Yu et al., 2005 [PubMed 15674325]).[supplied by OMIM, Mar 2008] Function: May play a role in cell proliferation. May be required for the maintenance of cell cycle progression. Subcellular Location: Nucleus.Cytoplasm. Tissue Specificity: Highly expressed in spleen and thymus. Intermediate levels in liver, kidney, pancreas, prostate, testis, ovary, intestine, and leukocytes. Low expression in heart, brain, placenta, lung, skeletal muscle, and colon. Post-translational modifications: Stimulated through its phosphorylation by CDK2. Acquires CDK-dependent phosphorylation through late-G1 to S phase, and from prometaphase to cytokinesis in the nucleolar organizing regions. Phosphorylation is suppressed in growth-arrested cells. Similarity: Contains 1 PARP catalytic domain. Database links: Entrez Gene: 84875 Human Entrez Gene: 671535 Mouse Omim: 609564 Human SwissProt: Q53GL7 Human Unigene: 348609 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
