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Rabbit Anti-PCDH19/BF488 Conjugated antibody (bs-19911R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-19911R-BF488
英文名稱 Rabbit Anti-PCDH19/BF488 Conjugated antibody
中文名稱 BF488標記的原鈣粘附蛋白19抗體
別    名 KIAA1313; PCD19_HUMAN; PCDH19; Protocadherin 19; Protocadherin-19.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  細胞粘附分子  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,  (predicted: Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 124kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PCDH19
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The protein encoded by this gene is a member of the delta-2 protocadherin subclass of the cadherin superfamily. The encoded protein is thought to be a calcium-dependent cell-adhesion protein that is primarily expressed in the brain. Defects in this gene are a cause of epilepsy female-restricted with mental retardation (EFMR). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]

Function:
Potential calcium-dependent cell-adhesion protein.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Moderately expressed in all regions of the brain examined, with lowest levels found in the cerebellum. Moderate expression is also found in ovary, and low expression in all other tissues tested. Also detected in primary skin fibroblast.

DISEASE:
Epileptic encephalopathy, early infantile, 9

Similarity:
Contains 6 cadherin domains.

Database links:

Entrez Gene: 57526 Human

Entrez Gene: 101125719 Gorilla

Entrez Gene: 100059478 Horse

Entrez Gene: 279653 Mouse

Omim: 300460 Human

SwissProt: Q8TAB3 Human

SwissProt: Q80TF3 Mouse

Unigene: 4993 Human

Unigene: 39738 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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