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Rabbit Anti-SH3BP5/AP Conjugated antibody (bs-19752R-AP)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-19752R-AP
英文名稱 Rabbit Anti-SH3BP5/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的SH3結構域結合蛋白5抗體
別    名 3BP5_HUMAN; OTTHUMP00000208289; OTTHUMP00000208291; OTTHUMP00000208294; SAB; SH3 binding protein; SH3 domain binding protein 5 (BTK associated); SH3 domain binding protein 5; SH3 domain binding protein that preferentially associates with BTK; SH3 domain-binding protein 5; SH3 domain-binding protein that preferentially associates with BTK; SH3 domainbinding protein 5; SH3BP 5; SH3BP-5; Sh3bp5.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  細胞凋亡  激酶和磷酸酶  淋巴細胞  b-淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse,  (predicted: Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, )
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SH3BP5
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.

Subcellular Location:
Mitochondrion.

Tissue Specificity:
Highly expressed in testis and ovaries. It is also expressed in a variety of tissues including spleen, lymph node, thymus, bone marrow, fetal liver, colon, small intestine and prostate.

Similarity:
Belongs to the SH3BP5 family.

Database links:

Entrez Gene: 9467 Human

Entrez Gene: 520254 Cow

Entrez Gene: 80851 Human

Entrez Gene: 24056 Mouse

Entrez Gene: 79566 Mouse

Entrez Gene: 117186 Rat

Omim: 605612 Human

SwissProt: Q0V8K7 Cow

SwissProt: O60239 Human

SwissProt: Q7L8J4 Human

SwissProt: Q99LH9 Mouse

SwissProt: Q9Z131 Mouse

SwissProt: Q91Y80 Rat

Unigene: 11005 Cow

Unigene: 257761 Human

Unigene: 726063 Human

Unigene: 290534 Mouse

Unigene: 383198 Mouse

Unigene: 163321 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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