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Rabbit Anti-PLD3/BF488 Conjugated antibody (bs-12717R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-12717R-BF488
英文名稱 Rabbit Anti-PLD3/BF488 Conjugated antibody
中文名稱 BF488標記的膽堿磷酸酯酶3抗體
別    名 Choline phosphatase 3; HindIII K4L homolog; HU K4; Hu-K4; HUK4; Phosphatidylcholine hydrolyzing phospholipase D3; Phosphatidylcholine-hydrolyzing phospholipase D3; Phospholipase D family, member 3; Phospholipase D3; PLD 3; PLD3; PLD3_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  神經生物學  信號轉導  Alzheimer's  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Cow, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 55kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PLD3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a member of the phospholipase D (PLD) family of enzymes that catalyze the hydrolysis of membrane phospholipids. The encoded protein is a single-pass type II membrane protein and contains two PLD phosphodiesterase domains. This protein influences processing of amyloid-beta precursor protein. Mutations in this gene are associated with Alzheimer disease risk. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Apr 2014]

Subcellular Location:
Endoplasmic reticulum membrane.

Tissue Specificity:
Widely expressed. Expressed at higher level in brain. Expressed at low level in corpus callosum, suggesting that it is highly expressed in neurons.

Post-translational modifications:
Glycosylated.

Similarity:
Belongs to the phospholipase D family.
Contains 2 PLD phosphodiesterase domains.

Database links:

Entrez Gene: 23646 Human

Entrez Gene: 18807 Mouse

Entrez Gene: 361527 Rat

SwissProt: Q2KJJ8 Cow

SwissProt: Q8IV08 Human

SwissProt: O35405 Mouse

SwissProt: Q5FVH2 Rat

Unigene: 257008 Human

Unigene: 6483 Mouse

Unigene: 128036 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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