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Rabbit Anti-PEBP4/BF488 Conjugated antibody (bs-12610R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-12610R-BF488
英文名稱 Rabbit Anti-PEBP4/BF488 Conjugated antibody
中文名稱 BF488標記的磷脂酰乙醇胺結合蛋白4抗體
別    名 1700051A02Rik; 1700081D17Rik; AI429082; CORK 1; CORK1; Cousin of RKIP 1 protein; GWTM1933; hPEBP4; MGC22776; PEBP 4; Phosphatidylethanolamine binding protein 4; PRO4408; Protein cousin of RKIP 1; UNQ1933/PRO4408.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  細胞凋亡  激酶和磷酸酶  結合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 26kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PEBP4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The phosphatidylethanolamine (PE)-binding proteins, including PEBP4, are an evolutionarily conserved family of proteins with pivotal biologic functions, such as lipid binding and inhibition of serine proteases (Wang et al., 2004 [PubMed 15302887]).[supplied by OMIM, Dec 2008]

Function:
Seems to promote cellular resistance to TNF-induced apoptosis by inhibiting activation of the Raf-1/MEK/ERK pathway, JNK and phosphatidylethanolamine externalization

Subcellular Location:
Lysosome

Tissue Specificity:
Ubiquitously expressed. Highly expressed in tumor cells.

Similarity:
Belongs to the phosphatidylethanolamine-binding protein family.

Database links:

Entrez Gene: 157310 Human

Omim: 612473 Human

SwissProt: Q96S96 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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