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Rabbit Anti-ZMIZ2/APC Conjugated antibody (bs-4391R-APC)
訂購熱線:400-901-9800
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訂購QQ:  400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-4391R-APC
英文名稱 Rabbit Anti-ZMIZ2/APC Conjugated antibody
中文名稱 APC標記的鋅指MIZ結構域蛋白2抗體
別    名 2410117E06Rik; D11Bwg0280e; DKFZp761I2123; hZIMP7; KIAA1886; PIAS like protein Zimp7; PIAS-like protein Zimp7; R74931; RGD1309256; RP23-198N14.8; ZIMP7; Zinc finger MIZ domain containing protein 2; Zinc finger MIZ domain-containing protein 2; Zinc finger MIZ type containing 2; zinc finger, MIZ-type containing 2; zinc finger, MIZtype containing2; ZMIZ 2; Zmiz2; ZMIZ2_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 轉錄調節因子  鋅指蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Rabbit, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 97kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZMIZ2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with nuclear hormone receptors. ZMIZ2 interacts with androgen receptor (AR; MIM 313700) and enhances AR-mediated transcription (Huang et al., 2005 [PubMed 16051670]).[supplied by OMIM, May 2010]

Function:
Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors.

Subcellular Location:
Nucleus. Detected at replication foci throughout S phase.

Tissue Specificity:
Expressed most abundantly in testis with lower levels in heart, brain, pancreas, prostate and ovary.

Similarity:
Contains 1 SP-RING-type zinc finger.

Database links:

Entrez Gene: 83637 Human

Entrez Gene: 52915 Mouse

Entrez Gene: 289783 Rat

Entrez Gene: 6378 Rat

Omim: 611196 Human

SwissProt: Q8NF64 Human

SwissProt: Q8CIE2 Mouse

Unigene: 600681 Human

Unigene: 77978 Human

Unigene: 1144 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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