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Rabbit Anti-RALGPS2/BF488 Conjugated antibody (bs-21178R-BF488)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-21178R-BF488
英文名稱 Rabbit Anti-RALGPS2/BF488 Conjugated antibody
中文名稱 BF488標(biāo)記的RALGPS2蛋白抗體
別    名 dJ595C2.1; FLJ10244; FLJ25604; KIAA0351; Ral A exchange factor RalGPS2; Ral GEF with PH domain and SH3 binding motif 2; RALGPS 2; ras-specific guanine nucleotide-releasing factor RalGPS2.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 65kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RALGPS2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
RalGPS2 (Ral GEF with PH domain and SH3 binding motif 2) is a guanine nucleotide exchange factor for RalA GTPase. It is expressed in testis and brain.

Function:
Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity).

Subunit:
Interacts with the SH3 domains of GRB2 and PLCG1. Interacts with RALA.

Subcellular Location:
Cell Membrane and Cytoplasmic. Associates with membranes through the PH domain.

DISEASE:
RALGPS2 is a potential candidate gene for susceptibility to Alzheimer disease linked to 1q24.

Database links:

Entrez Gene: 424429 Chicken

Entrez Gene: 457549 Chimpanzee

Entrez Gene: 100052879 Horse

Entrez Gene: 55103 Human

Entrez Gene: 78255 Mouse

Entrez Gene: 304887 Rat

Entrez Gene: 717165 Rhesus monkey

Entrez Gene: 779506 Xenopus tropicalis

Entrez Gene: 393446 Zebrafish

SwissProt: Q5ZJK0 Chicken

SwissProt: Q4R7W3 Cynomolgus Monkey

SwissProt: Q86X27 Human

SwissProt: Q9ERD6 Mouse

Unigene: 632485 Human

Unigene: 28376 Mouse

Unigene: 224486 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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