97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號(hào)           掃碼咨詢(xún)技術(shù)支持           掃碼咨詢(xún)技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
性色av网址,国产精品高潮视频,91极品在线
Rabbit Anti-DEF6/IBP/AP Conjugated antibody (bs-20306R-AP)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-20306R-AP
英文名稱(chēng) Rabbit Anti-DEF6/IBP/AP Conjugated antibody
中文名稱(chēng) 堿性磷酸酶(AP)標(biāo)記的干擾素調(diào)節(jié)因子4結(jié)合蛋白抗體
別    名 DEF-6; Def6; DEFI6_HUMAN; Differentially expressed in FDCP 6 homolog; Differentially expressed in FDCP 6 homologue mouse; IBP; IRF4-binding protein; Swap70 like adapter of T cells.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  G蛋白信號(hào)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Rat,  (predicted: Human, Mouse, Rabbit, )
產(chǎn)品應(yīng)用 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 74kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DEF6/IBP
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
DEF6 is a 631 amino acid protein that is widely expressed in T and B cells of the immune system. Localized to the nucleus, cytoplasm and cell membrane, DEF6 is a phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) that functions to activate Rho GTPases such as Rac 1, Cdc42 and Rho A. Via its ability to activate various Rho GTPases, DEF6 can regulate cell shape, movement and polarity and, through its interaction with T helper cells, DEF6 can also help mediate the immune response. DEF6 contains one PH (pleckstrin homology) domain which is required for binding to phosphatidylinositol 3,4,5-trisphosphate and subsequent recruitment to the plasma membrane.

Function:
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which plays a role in the activation of Rho GTPases RAC1, RhoA and CDC42. Can regulate cell morphology in cooperation with activated RAC1. Plays a role in Th2 (T helper cells) development and/or activation, perhaps by interfering with ZAP-70 signaling.

Subunit:
Interacts with ZAP70 (By similarity). Interacts with IRF4, activated RAC1 and F-actin. Both the phosphorylated and non-phosphorylated forms bind phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3).

Subcellular Location:
Cytoplasm. Cell membrane. Nucleus. Recruited to the plasma membrane upon binding phosphatidylinositol 3,4,5-trisphosphate.

Tissue Specificity:
Broadly expressed in the immune system and can be detected in T and B-cells.

Post-translational modifications:
Tyrosine-phosphorylated by tyrosine-protein kinase LCK in response to T-cell activation.

Similarity:
Contains 1 PH domain.

Database links:

Entrez Gene: 50619 Human

Entrez Gene: 23853 Mouse

Entrez Gene: 309642 Rat

Omim: 610094 Human

SwissProt: Q9H4E7 Human

SwissProt: Q8C2K1 Mouse

Unigene: 15476 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 说英雄谁是英雄免费观看 | 亚洲欧美日韩天堂一区二区 | 岛国a视频在线观看免费18在线看 | 蜜桃视频无码区在线观看 | 韩日免费 | 91丨porny丨九色 | 在线不卡视频 | 欧美日韩在线一二三 | 欧美黄色一级片视频 | 无码精品A∨在线观看中文 国产午夜精品片一区二区三区 | 国产精品毛片一区视频播 | 天天做天天爱夜夜爽女人爽 | 亚洲视频一区国产 | 日日摸夜夜添夜夜添无码免费视频 | 人人妻人人澡人人爽人人精品AV | 熟妇性hqmaturetube| 天天爱天天做天天添天天欢 | 啊v视频| 久久韩日| 欧美国产精品久久久 | 92精品国产自产在线观看481页 | 肉岳疯狂69式激情的高潮 | 天堂а在线最新版在线 | 一本一本久久A久久综合精品蜜桃 | 亚洲国产成人久久综合人 | 成人精品福利视频 | 日本精品一区二区三区视频 | 天天摸日日添狠狠添婷婷 | 中文字幕一区二区三区乱码在线 | 四虎影视永久免费在线观看 | 国内精品国产成人国产三级李采潭 | 亚洲AV无码精品色午夜蜜芽 | 动漫精品视频一区二区三区 | 精品无码AV无码专区 | 成年肉动漫在线观看无码 | 男人扒开女人腿喷水视频 | 91酒色 | 91精选在线 | 东京复仇者第三季天竺篇在线观看 | 91久久一区二区 | 很黄的网站在线观看 |