97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
wwwww国产,japan欧美性xxxx24,国产偷国产偷av亚洲清高
Mouse Anti-phospho-MLKL (Ser358)/RBITC Conjugated antibody (bsm-33331M-RBITC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bsm-33331M-RBITC
英文名稱 Mouse Anti-phospho-MLKL (Ser358)/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標(biāo)記的磷酸化MLKL單克隆抗體
別    名 phospho-MLKL(S358); p-MLKL(S358); MLKL(p-S358);9130019I15Rik; FLJ34389; hMLKL; Mixed lineage kinase domain like; Mixed lineage kinase domain like protein; Mixed lineage kinase domain-like protein; MLKL_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  激酶和磷酸酶  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號(hào) 8C4
交叉反應(yīng)
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 54kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human phospho-MLKL (Ser358)
亞    型 IgG
純化方法 affinity purified by Protein G
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2015].

Function:
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

Subunit:
Homotrimer; forms homotrimers on necroptosis induction. Interacts with RIPK3; the interaction is direct. Upon TNF-induced necrosis, forms in complex with PGAM5, RIPK1 and RIPK3. Within this complex, may play a role in the proper targeting of RIPK1/RIPK3 to its downstream effector PGAM5.

Subcellular Location:
Cytoplasm. Cell membrane. Note=Localizes to the cytoplasm and translocates to the plasma membrane on necroptosis induction.

Post-translational modifications:
Phosphorylation by RIPK3 induces a conformational switch that is required for necroptosis. It also induces homotrimerization and localization to the plasma membrane.

Similarity:
Belongs to the protein kinase superfamily.
Contains 1 protein kinase domain.

Database links:

Entrez Gene: 197259 Human

Entrez Gene: 74568 Mouse

Entrez Gene: 690743 Rat

Omim: 615153 Human

SwissProt: Q8NB16 Human

SwissProt: Q9D2Y4 Mouse

Unigene: 119878 Human

Unigene: 207971 Mouse

Unigene: 105677 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 四虎影视在线影院在线观看 | 永久亚洲成a人片777777 | 亚洲国产精品成人精品无码区在线 | 国产精品无码在线 | 新久草在线视频 | 无码专区男人本色 | 91视频porny | 欧美精品一本久久男人的天堂 | 欧美在线视频一区二区 | 久久精品一区二区三区视频 | 深夜免费观看视频 | 国产亚洲精品欧洲在线观看 | 精品熟女碰碰人人A久久 | 暴力调教一区二区三区 | 亚洲欧美日韩在线观看一区二区三区 | 亚洲成人资源在线观看 | 91精品在线免费视频 | 欧美国产精品日韩在线 | 国产精品网站在线观看 | 麻豆安全免费网址入口 | www.一区二区三区.com | 亚洲国产99在线精品一区二区 | 国产成人欧美一区二区三区一色天 | 国产欧美日韩另类色视频云霸 | 国产在线观看香蕉视频网 | 顶级少妇做爰视频在线观看 | 好爽好黄好刺激的视频 | 农村少妇无套内谢粗又长 | 久久天天躁狠狠躁夜夜96流白浆 | 天天躁日日躁狠狠躁aab吃奶 | 日本成人在线免费视频 | 国产偷窥熟妇高潮呻吟 | 97免费视频在线观看 | 火影大胸美女被黄网站 | 欧美性猛交久久久乱大交小说 | 国产毛片毛片毛片毛片毛片 | 久久亚洲精品无码爱剪辑 | 欧美极品视频 | 天堂在线最新版 | 免费无码成人AV片在线在线播放 | 变形金刚之超能勇士免费观看 |