97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
日日摸日日,免费毛片av,2024最新毛片
Rabbit Anti-EPB41/Gold Conjugated antibody (bs-20591R-Gold)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-20591R-Gold
英文名稱 Rabbit Anti-EPB41/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的紅細(xì)胞膜條帶4.1蛋白抗體
別    名 4.1R; 41_HUMAN; Band 4.1; E41P; EL 1; EL1; Elliptocytosis 1; Elliptocytosis 1 RH linked; EPB 4.1; EPB 41; EPB4.1; Epb41; Erythrocyte membrane protein band 4.1 (elliptocytosis 1 RH linked); Erythrocyte membrane protein band 4.1; Erythrocyte surface protein band 4.1; HE; P4.1; Protein 4.1.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞骨架  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng)
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 97kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human EPB41
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
The 4.1 gene family encodes a group of multifunctional cytoskeletal proteins (4.1R, 4.1G, 4.1N and 4.1B), which are predominantly expressed in the nervous system. 4.1G is a protein that stabilizes spectrin-actin interactions and is associated with hereditary elliptocytosis. Red blood cell 4.1, designated 4.1R, is a multifunctional protein that is essential for maintaining erythrocyte shape and membrane mechanical properties. Both 4.1R and 4.1G are distributed in a unique pattern in the cerebellum and are believed to modulate the membrane mechanical properties of neuronal cells by promoting fodrin/actin association. 4.1N and 4.1B, designated EPB41L1 and EPB41L3, respectively, are strongly expressed in the brain. Antibodies to 4.1N have been reported to detect mulitple forms, each enriched in postsynaptic density preparations relative to brain homogenate. Antibodies to 4.1B have been reported to detect two forms.

Function:
Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes.

Subcellular Location:
Cytoplasm > cytoskeleton. Cytoplasm > cell cortex. Nucleus.

Post-translational modifications:
Phosphorylated at multiple sites by different protein kinases and each phosphorylation event selectively modulates the protein's functions.
Phosphorylation on Tyr-660 reduces the ability of 4.1 to promote the assembly of the spectrin/actin/4.1 ternary complex.
O-glycosylated; contains N-acetylglucosamine side chains in the C-terminal domain.

DISEASE:
Defects in EPB41 are the cause of elliptocytosis type 1 (EL1) [MIM:611804]. EL1 is a Rhesus-linked form of hereditary elliptocytosis, a genetically heterogeneous, autosomal dominant, hematologic disorder. It is characterized by variable hemolytic anemia and elliptical or oval red cell shape. Defects in EPB41 are a cause of hereditary pyropoikilocytosis (HPP) [MIM:266140]. HPP is an autosomal recessive hematologic disorder characterized by hemolytic anemia, microspherocytosis, poikilocytosis, and an unusual thermal sensitivity of red cells.

Similarity:
Contains 1 FERM domain.

Database links:

Entrez Gene: 2035 Human

Entrez Gene: 269587 Mouse

Omim: 130500 Human

SwissProt: P11171 Human

SwissProt: P48193 Mouse

Unigene: 175437 Human

Unigene: 708933 Human

Unigene: 712722 Human

Unigene: 30038 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 国产精品视频观看 | 国产迷晕暴力玩弄网站 | 东京复仇者第三季天竺篇在线观看 | 日韩黄色免费观看 | 成人性做爰 | 9191久久久久久久久久久 | 中日韩亚洲人成无码网站 | 2023国产一二三区日本精品2022 | 中文字幕第50页 | 国产成人久久综合777777麻豆 | 免费观看黃色A一级视频日本 | 日韩欧美成人一区二区三区 | 精品在线观看一区二区三区 | 亚洲最大天堂网 | 少妇69xx| 一区二区三区视频免费视频观看网站 | 午夜影院免费观看 | 亚洲丁香婷婷久久一区二区 | 日本高清不卡中文字幕免费 | www.51色.com| 99午夜| 日韩毛片免费视频一级特黄 | 精品久久999 | 午夜爽爽爽男女免费观看影院 | av免费网| 欧美最猛性| 日韩第一夜| 肥美欧美内射中出 | 亚洲成av人片在线观看无码不卡 | 日本午夜在线观看 | www.日韩有码 | 国产精品日韩AV在线播放 | 在线看一级毛片 | 色老板精品视频在线观看 | 亚洲精品综合第一国产综合 | 久久久久久国产精品免费免费狐狸 | xxxx交换夫妇com1 | 少妇小莹的yin荡生活下视频 | 91夜夜蜜桃臀一区二区三区 | 日韩av中文字幕第一页 | 性伦欧美刺激片在线观看 |