97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
亚洲剧场午夜在线观看,国产粉嫩在线,黄色片网站免费在线观看
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-CD44v10/BF594 Conjugated antibody (bs-13975R-BF594)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13975R-BF594
英文名稱 Rabbit Anti-CD44v10/BF594 Conjugated antibody
中文名稱 BF594標記的CD44V10抗體
別    名 IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CDW44; CSPG8; HCELL; HUTCH-I; ECMR-III  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  干細胞  細胞粘附分子  細胞表面分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, 
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52/82kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD44v10
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008].

Function:
Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.

Subunit:
Interacts with PKN2. Interacts with HA, as well as other glycosaminoglycans, collagen, laminin, and fibronectin via its N-terminal segment. Interacts with ANK, the ERM proteins (VIL2, RDX and MSN), and NF2 via its C-terminal segment.

Subcellular Location:
Membrane; Single-pass type I membrane protein. Note=Colocalizes with actin in membrane protrusions at wounding edges.

Tissue Specificity:
Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas. Expression is repressed in neuroblastoma cells.

Post-translational modifications:
Proteolytically cleaved in the extracellular matrix by specific proteinases (possibly MMPs) in several cell lines and tumors.
N- and O-glycosylated. O-glycosylation contains more-or-less-sulfated chondroitin sulfate glycans, whose number may affect the accessibility of specific proteinases to their cleavage site(s). It is uncertain if O-glycosylation occurs on Thr-637 or Thr-638.
Phosphorylated; activation of PKC results in the dephosphorylation of Ser-706 (constitutive phosphorylation site), and the phosphorylation of Ser-672.

Similarity:
Contains 1 Link domain.

Database links:

Entrez Gene: 960 Human

Omim: 107269 Human

SwissProt: P16070 Human

Unigene: 502328 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 一区二区观看 | 国产欧美日产久久 | 玩弄JAPAN白嫩少妇HD小说 | 成人欧美大片免费观看 | 国产黄色免费在线视频 | 午夜精品区 | 中文字幕麻豆 | 欧美人免费视频网站在线 | 久久九色 | 女人和拘做受全程看免费软件 | 亚洲天堂中文 | 精品国产欧美日韩不卡在线观看 | 三区四区乱码不卡 | 国产无区一区二区三麻豆 | 色哟哟~日韩精品 | 亚洲色精品VR一区二区 | 色综合久久精品 | 亚洲国产精品一区二区久久亚洲午夜 | 亚洲日韩爆乳中文字幕欧美 | 国产二级一片内射视频播放 | 日日碰狠狠躁久久躁蜜桃 | 久久久国产精品萌白酱免费 | 日产精品久久久 | 女同久久精品国产99国产精品网站 | 美女一区二区久久 | 91九色论坛 | 国产在线欧美日韩精品一区 | 亚洲AV日韩AV国内 | 午夜一二区 | 亚洲国产成人综合一区二区三区 | 日韩精品资源在线 | 亚洲久久成人 | 国产精品一区二区免费久久精品 | 日本牲交大片免费观看 | 蜜臀人妻精品一区二区免费 | 日本拍拍免费观看片成人 | 亚洲男人天堂久久 | 91亚洲精品第一 | 日日天天| 精品国产欧美一区二区三区不卡 | 成人午夜免费无码视频在线观看 |