97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質(zhì)量反饋  關于我們  聯(lián)系我們
www.se小姐.com,日韩黄大片,青青草在线免费
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-CD14/BF488 Conjugated antibody (bs-20796R-BF488)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-20796R-BF488
英文名稱 Rabbit Anti-CD14/BF488 Conjugated antibody
中文名稱 BF488標記的內(nèi)毒素受體抗體
別    名 CD14 antigen; CD14 molecule; Lipopolysaccharide receptor; LPSR; Monocyte Differentiation Antigen 14; Monocyte differentiation antigen CD14; Myeloid cell specific leucine rich glycoprotein; CD14_HUMAN; Myeloid cell-specific leucine-rich glycoprotein.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 轉錄調(diào)節(jié)因子  細胞膜受體  糖尿病  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, 
產(chǎn)品應用 Flow-Cyt=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 35/40kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD14
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
CD14 is a single copy gene encoding 2 protein forms: a 50 to 55 kDa glycosylphosphatidylinositol anchored membrane protein (mCD14) and a monocyte or liver derived soluble serum protein (sCD14) that lacks the anchor. Both molecules are critical for lipopolysaccharide (LPS) dependent signal transduction, and sCD14 confers LPS sensitivity to cells lacking mCD14. Increased sCD14 levels are associated with inflammatory infectious diseases and high mortality in gram negative shock. CD14 also appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.

Function:
Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.

Subunit:
Belongs to the lipopolysaccharide (LPS) receptor, a multi-protein complex containing at least CD14, MD-2 and TLR4.

Subcellular Location:
Cell membrane; Lipid-anchor, GPI-anchor.

Similarity:
Contains 11 LRR (leucine-rich) repeats.

Database links:

Entrez Gene: 929 Human

Entrez Gene: 12475 Mouse

Omim: 158120 Human

SwissProt: P08571 Human

Unigene: 163867 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CD14又稱內(nèi)毒素受體,屬細胞表面糖蛋白家族成員之一。在機體免疫、防御系統(tǒng)引起的一系列反應中介導細胞識別LPS并引起細胞酪氨酸磷酸化、核因子NF-κB轉位、觸發(fā)細胞因子釋放和氧自由基產(chǎn)生。CD14在細胞因子產(chǎn)生的調(diào)控方面起重要作用,因而對于CD14結構、功能及其臨床意義的研究日益受到重視。
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 大肉大捧一进一出好爽 | 护士故意露出奶头让我吃奶 | 在线视频1区 | 欧美精品久久久久 | 色婷婷综合久久久久中国一区二区 | 免费碰碰视频在线观看 | 亚洲天堂精品在线观看 | 中文无码一区二区视频在线播放 | 69免费网站 | 久久久品 | chinese裸体男野外gay | 国内外精品激情刺激在线 | 裸体女人高潮毛片扒开一一区 | 中文字幕av一区二区三区人 | japanese国产打屁股网站 | 50丰满少妇高潮惨叫正在播放 | 内射巨臀欧美在线视频 | 精品一区二区三区日本 | 少妇bbbb水多毛片人 | 免费国产黄线在线播放 | 最新日韩AV网址在线观看 | 天天搞美女视频 | 国产午夜亚洲精品 | 午夜嘿嘿| 国产精品一区二区三区久久久久 | 一区二区国产精品 | 欧美日韩中文字幕在线 | 日本神影院一区二区三区 | 日本一区二区三区视频中文字幕 | 亚洲精品一区二区网址 | 亚洲AV无码日韩AV无码网站冲 | 一区二区三区日本 | 东北老女人高潮疯狂过瘾对白 | 国内精品自产拍在线观看 | 欧美一区二区三区少妇 | 铜铜铜铜铜铜铜铜好大无打码 | 美丽姑娘免费高清观看 | 日韩第十页 | 好大好爽好深国产在线 | 欧美综合一区 | 国产成人AV性色在线影院色戒 |