97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
欧美视频在线观看视频,国产精品国产,日韩有码片
首頁 > 產品中心 > 標記一抗 > 產品信息
Mouse Anti-CD41/Integrin alpha 2b/PE-Cy5.5 Conjugated antibody (bsm-33112M-PE-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bsm-33112M-PE-Cy5.5
英文名稱 Mouse Anti-CD41/Integrin alpha 2b/PE-Cy5.5 Conjugated antibody
中文名稱 PE-Cy5.5標記的CD41/血小板膜糖蛋白Ⅱb單克隆抗體
別    名 platelet glycoprotein IIb of IIb/IIIa complex; Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); ITGA2B; GPIIb; GTA; HPA3; CD 41; CD41; CD41 antigen; CD41a; CD41b; GP2b; GPalpha IIb; GPalphaIIb; Integrin alpha IIb; Integrin alpha IIb precursor; ITGA 2B; ITGA2B; ITGAB; Platelet fibrinogen receptor alpha; Platelet fibrinogen receptor alpha subunit; Platelet glycoprotein IIb of IIb/IIIa complex; Platelet membrane glycoprotein IIb; Platelet specific antigen bak; ITA2B_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  免疫學  信號轉導  細胞粘附分子  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 9B10
交叉反應 (predicted: Human, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 125kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD41/Integrin alpha 2b
亞    型 IgG
純化方法 affinity purified by Protein G
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.05M PB, pH 7.5.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.

Function:
Isoform 1 and isoform 2 were identified in platelets and megakaryocytes, but not in reticulocytes or in Jurkat and U937 white blood cell line. Isoform 3 is expressed by leukemia, prostate adenocarcinoma and melanoma cells but not by platelets or normal prostate or breast epithelial cells.

Subcellular Location:
Membrane.

DISEASE:
Defects in ITGA2B are a cause of Glanzmann thrombasthenia (GT) [MIM:273800]; also known as thrombasthenia of Glanzmann and Naegeli. GT is the most common inherited disease of platelets. It is an autosomal recessive disorder characterized by mucocutaneous bleeding of mild-to-moderate severity and the inability of this integrin to recognize macromolecular or synthetic peptide ligands. GT has been classified clinically into types I and II. In type I, platelets show absence of the glycoprotein IIb/beta-3 complexes at their surface and lack fibrinogen and clot retraction capability. In type II, the platelets express the glycoprotein IIb/beta-3 complex at reduced levels (5-20% controls), have detectable amounts of fibrinogen, and have low or moderate clot retraction capability. The platelets of GT 'variants' have normal or near normal (60-100%) expression of dysfunctional receptors.

Similarity:
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.

Database links:

Entrez Gene: 3674 Human

Entrez Gene: 16399 Mouse

Entrez Gene: 685269 Rat

Omim: 607759 Human

SwissProt: P08514 Human

SwissProt: Q9QUM0 Mouse

Unigene: 411312 Human

Unigene: 26646 Mouse

Unigene: 128177 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 色婷婷成人综合激情免费视频 | 香蕉97超级碰碰碰视频 | 乱人伦中文字幕 | 国产欧美一区二区精品仙草咪 | 国内一区二区视频 | 国精品无码一区二区三区在线 | 男女性高爱潮免费网站 | 国产香蕉一区二区在线网站 | 在教室伦流澡到高潮H强圩动漫 | 一级做a爰片性色毛片是免费 | 丁香花在线观看免费观看 | 日日噜狠狠噜天天噜AV | 精品福利在线观看 | 国产精成人品 | 日韩精品成人一区二区三区 | 日韩一二三区在线 | 99在线视频免费 | 无遮无挡爽爽免费视频 | 色第一页 | 亚人在线播放国产中文字幕 | 成人国产精品一区在线观看播放 | 熟妇人妻AV中文字幕老熟妇 | 一区二区视频免费看 | 无码被窝影院午夜看片爽爽JK | 成人黄网视频在线观看 | 38激情网 | 激情av无码后入 | 日本www免费视频网站在线观看 | 美女扒开腿让男人桶爽网站 | 国产色播av在线 | 4399理论片午午伦夜理片 | 国产一二三区在线观看 | 国产真实老熟女无套内射 | CHINESE国产老熟女 | 国产精品无码专区网站 | 色欲色欲天天天WWW亚洲伊 | 91久久精品一 | 人人超碰人人爱超碰国产 | 成人免费高清在线播放 | 精品日本一区二区三区免费 | 久久精品国产亚洲av麻豆小说 |