97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
欧美视频在线观看视频,国产精品国产,日韩有码片
首頁 > 產品中心 > 標記一抗 > 產品信息
Mouse Anti-CD41/Integrin alpha 2b/PE-Cy5.5 Conjugated antibody (bsm-33112M-PE-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bsm-33112M-PE-Cy5.5
英文名稱 Mouse Anti-CD41/Integrin alpha 2b/PE-Cy5.5 Conjugated antibody
中文名稱 PE-Cy5.5標記的CD41/血小板膜糖蛋白Ⅱb單克隆抗體
別    名 platelet glycoprotein IIb of IIb/IIIa complex; Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); ITGA2B; GPIIb; GTA; HPA3; CD 41; CD41; CD41 antigen; CD41a; CD41b; GP2b; GPalpha IIb; GPalphaIIb; Integrin alpha IIb; Integrin alpha IIb precursor; ITGA 2B; ITGA2B; ITGAB; Platelet fibrinogen receptor alpha; Platelet fibrinogen receptor alpha subunit; Platelet glycoprotein IIb of IIb/IIIa complex; Platelet membrane glycoprotein IIb; Platelet specific antigen bak; ITA2B_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  免疫學  信號轉導  細胞粘附分子  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 9B10
交叉反應 (predicted: Human, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 125kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD41/Integrin alpha 2b
亞    型 IgG
純化方法 affinity purified by Protein G
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.05M PB, pH 7.5.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.

Function:
Isoform 1 and isoform 2 were identified in platelets and megakaryocytes, but not in reticulocytes or in Jurkat and U937 white blood cell line. Isoform 3 is expressed by leukemia, prostate adenocarcinoma and melanoma cells but not by platelets or normal prostate or breast epithelial cells.

Subcellular Location:
Membrane.

DISEASE:
Defects in ITGA2B are a cause of Glanzmann thrombasthenia (GT) [MIM:273800]; also known as thrombasthenia of Glanzmann and Naegeli. GT is the most common inherited disease of platelets. It is an autosomal recessive disorder characterized by mucocutaneous bleeding of mild-to-moderate severity and the inability of this integrin to recognize macromolecular or synthetic peptide ligands. GT has been classified clinically into types I and II. In type I, platelets show absence of the glycoprotein IIb/beta-3 complexes at their surface and lack fibrinogen and clot retraction capability. In type II, the platelets express the glycoprotein IIb/beta-3 complex at reduced levels (5-20% controls), have detectable amounts of fibrinogen, and have low or moderate clot retraction capability. The platelets of GT 'variants' have normal or near normal (60-100%) expression of dysfunctional receptors.

Similarity:
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.

Database links:

Entrez Gene: 3674 Human

Entrez Gene: 16399 Mouse

Entrez Gene: 685269 Rat

Omim: 607759 Human

SwissProt: P08514 Human

SwissProt: Q9QUM0 Mouse

Unigene: 411312 Human

Unigene: 26646 Mouse

Unigene: 128177 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 亚洲视频一区国产 | 久艹精品 | 色一欲一性一乱一区二区三区 | 大地资源免费 | 人人妻人人澡人人爽人人精品AV | 成人免费在线观看网站 | 亚洲国产成人精品无码一区二区 | 日韩不卡高清视频 | 天天色综| 国产美女久久久 | 国产精品国产三级国AV在线观看 | 91九色国产ts另类人妖 | 少妇下面好紧好爽视频 | 男人插女人免费视频 | 国产在线第一区 | 东京热无码av一区二区 | 日本黄网免费一区二区精品 | 中国丰满熟妇xxxx性 | 欧美一区二区三区在线看 | 日本一区二区福利视频 | 91tv官网精品成人亚洲 | 久久夜色精品国产欧美 | 国产精品r级最新在线观看 一区三区在线观看 | 99久久精品免费看国产免费软件 | 一区二区三区四区视频免费观看 | 97成人资源网 | 亚洲日本精品一区 | 欧美亚洲一级片 | 高清一区二区中文字幕 | 日本最黄视频 | 欧美一级片一区 | 无码人妻丰满熟妇精品区 | 国产97视频在线 | 黄色大片大毛片 | 亚洲色大成网站久久久 | 久久久久亚洲精品乱码按摩 | 新版天堂资源中文www官网 | 中文无码久久精品 | 欧美成人国产 | 男女后进式猛烈XX00免费视频 | 精品国产一区二区三区麻豆小说 |